Biopsy results corrected, Invasive Lobular Carcinoma

ltrinidad

Dear all,

After receiving a misleadingly benign biopsy report, someone corrected it and upgraded it to invasive lobular carcinoma. I am not sure how I feel. I have an MRI scheduled for next Monday and then genetic testing before surgery, to decide whether to go for a lumpectomy or mastectomy. Then radiation, then hormonal therapy. It is positive to estrogen and progesterone. I wish I could sleep through this all. Thank you for being there. Copying and pasting my results here:

Case Report	Surgical Biopsy Report Case: CB21-00667 Authorizing Provider: Kristine Pysarenko, MD Collected: 03/25/2021 1133 Ordering Location: NYU Langone Radiology at Received: 03/25/2021 1402 Perlmutter Cancer Center Pathologist: Osvaldo J Hernandez, MD Specimen: Breast, right
Correction Reason	The case was amended to revise the diagnosis from "complex sclerosing lesion/radial scar" to "invasive lobular carcinoma, moderately differentiated, classical type". Dr. Guth was notified this correction on April 7, 2021.
Addendum Reason: Biomarker Report	See biomarker report below
Final Diagnosis	Breast, right, 11:00, 4 cm from the nipple, ultrasound-guided core biopsy: - Invasive lobular carcinoma, moderately differentiated, classical type - Atypical lobular hyperplasia (ALH) - Fibrocystic changes with stromal fibrosis Comment: Immunostains for p63, Calponin and E-cadherin confirmed above diagnosis. This case was peer reviewed by Dr. Hernandez, who concurred with the diagnosis.
Synoptic Report	INVASIVE CARCINOMA OF THE BREAST: Biopsy (INVASIVE CARCINOMA OF THE BREAST: BIOPSY - All Specimens) Protocol posted: 4/29/2020 SPECIMEN Procedure: Needle biopsy Specimen Laterality: Right TUMOR Tumor Site: Clock position : 11 o'clock Tumor Site: Distance from nipple (Centimeters): 4 cm Histologic Type: Invasive lobular carcinoma Glandular (Acinar) / Tubular Differentiation: Score 3 Nuclear Pleomorphism: Score 2 Mitotic Rate: Score 1 Overall Grade: Grade 2 (scores of 6 or 7) Ductal Carcinoma In Situ (DCIS): Not identified Lymphovascular Invasion: Not identified Microcalcifications: Not identified Breast Biomarker Reporting Template ((Added in Addendum) BREAST: BIOMARKER REPORTING TEMPLATE - A) Protocol posted: 2/26/2020 Test(s) Performed: Estrogen Receptor (ER) Status: Positive (greater than 10% of cells demonstrate nuclear positivity) Percentage of Cells with Nuclear Positivity: 91-100% Average Intensity of Staining: Strong Test Type: Food and Drug Administration (FDA) cleared (test / vendor): Ventana Primary Antibody: SP1 Test(s) Performed: Progesterone Receptor (PgR) Status: Positive Percentage of Cells with Nuclear Positivity: 51-60% Average Intensity of Staining: Moderate Test Type: Food and Drug Administration (FDA) cleared (test / vendor): Ventana Primary Antibody: 1E2 Test(s) Performed: HER2 by Immunohistochemistry: Negative (Score 0) Test Type: Food and Drug Administration (FDA) cleared (test / vendor): Ventana Primary Antibody: 4B5 Test(s) Performed: Ki-67 Percentage of Cells with Nuclear Positivity: 5 % Primary Antibody: 30-9 Cold Ischemia and Fixation Times: Meet requirements specified in latest version of the ASCO / CAP Guidelines Testing Performed on Block Number(s): A1

2019whatayear

I am so sorry this happened.

ltrinidad

Thank you so much, 2019whatayear.

Dani444

I am so sorry for your diagnosis, especially after getting B9 results. What a roller coaster ride. The beginning is so overwhelming. It does actually get “easier” when you have a solid treatment plan in place. Glad they have scheduled an MRI for you. All the best to you, and don’t hesitate to ask any questions you might have.

moth

Oh I'm so sorry that this happened to you Only good thing is that they did find it in in the end - would have been horrible if they'd missed the staining and you did not get your diagnosis. Still sucks & what an awful roller coaster to be on. So upsetting

ltrinidad

Thank you so much, it means a lot to feel supported and understood. I will keep posting. Today was a long day. But I was prepared, in part thanks to this community. I hope you all have a nice weekend.

Rah2464

Ugh Itrinidad what an awful left turn. I am so very thankful that your pathology was reviewed and the error corrected , my goodness! One of the more difficult things about this process is you keep getting information by bits and pieces for a while so what you think might be the path can shift on you. Prayers that doesn't happen again for you on any level.

LivinLife

I can't imagine!!! I also agree with the others that thank goodness they caught the error, corrected it and you will be getting an appropriate plan soon! Soooo glad the support on this site has been so helpful and made a difference for you! Please update us as you can and certainly write in with any support needed, questions, etc....... Gentle hugs!