HER2 liver mets switch to triple negative liver mets

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FaithAndTrust
FaithAndTrust Member Posts: 44
edited February 2021 in Stage IV/Metastatic Breast Cancer, Open to All To Contribute

has this happened to anyone..or can anyone advise what options there are for this..?

many thanks in advance

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  • moth
    moth Member Posts: 4,800
    edited January 2021

    It's not very unusual for cancer to lose markers as it progresses. There is a liver mets thread you might want to see

    https://community.breastcancer.org/forum/8/topics/...

    as well as the triple neg stage IV thread https://community.breastcancer.org/forum/8/topics/...

    on p 93 of the triple neg stage IV thread, in the 4th post from the top I listed all the treatment options for us https://community.breastcancer.org/forum/8/topics/...

    generally with triple neg it will chemo &/or immunotherapy

    depending on size, location & number of the liver mets (plus your interventional radiologists' experience & treatment guidelines) local therapies such as ablation etc might be an option. We have a thread on liver ablative therapies here: https://community.breastcancer.org/forum/8/topics/...

    Do consider updating your profile so we can see the details of your dx and can provide more tailored info!

    best wishes

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  • FaithAndTrust
    FaithAndTrust Member Posts: 44
    edited January 2021

    Dear Moth thank you so much for your prompt response..I am actually posting for a dear friend who does not want to sift thru the forum herself right now as she finds she gets too distressed so I said I would do some research for her.

    I will go to page 93 of TN page now and have a look at the treatment options.

    she is awaiting genomic testing results before a plan is put in place for her.


    many thanks you are always a wealth of information 👍😉

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  • coolbluewater
    coolbluewater Member Posts: 15
    edited February 2021

    this happened to my sister as well. If you look through my post history, you will see she was in a clinical trial which proved effective against the TNBC liver mets. Unfortunately, she had progression in other areas and had to leave the trial but her liver has - knock wood - remained clear.

    I wish your friend the best.

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  • FaithAndTrust
    FaithAndTrust Member Posts: 44
    edited February 2021

    coolbluewater thank you so much for your reply. I am going to look at your posts now. Great to hear the trial did work for your sisters liver mets 👍

    I wish your sister all the very best going forward 🙏



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