Herceptin and Perjeta side effects after chemotherapy.

Nsbrown54

MinusTwo - I’ve been using systane lubricant eye drops at night and the refresh during the day. While my eyes are still dry, they have improved somewhat. I’ll check out the Thera Tears.

DeniseML

thanks for eye drop info. Last chemo was 12/8 and still experiencing eye tearing so am using Thera-tears now. It has helped! Does this mean I have been left with dry eye syndrome?

MinusTwo

Denise - I didn't think it was permanent. At least it wasn't for me. Since it's been 4 months, I'd definitely see what your MO says &/or make an appointment with an ophthalmologist.

DeniseML

I know this thread isn’t active right now, but, in case it’s viewed , I’m looking for anyone who experienced a worsening echocardiogram while on HP. I had to hold July dose for to a drop in my ejection fraction on echo. Can’t say I am feeling any different. Do you know if it will improve with holding a dose? Or can I expect to stop all infusions? I have 5 more to go, and this is concerning to me since there is no other recommended treatment for HER2+, IBC with pCR at time of surgery.

Melbo

sorry Denise — I don’t have any experience with heart issues from herceptin. I did want to share though that there have been studies showing that even six months of herceptin works — so even if you can’t finish the recommended number of Infusions it should still be okay. It does suck a lot though and I hope you will be able to pause and then finish the course.

https://www.breastcancer.org/research-news/herceptin-for-6-months-seems-same-as-1-yr

DeniseML

Melbo, thank-you for this information. I did not find this in my search! It does ease my mind a little to know it's been studied

Update: it’s a little over a year later. Continuing on cardiac meds. Heart muscle has slowly recovered. I opted not to finish HP treatment. NED to date. Just had PRM. Life moves on. Too many other things to take priority .

Hope & pray all of you are managing well and finding peace wherever you are at .

bakerb

Last year I completed 6 rounds of TCHP and experienced diarrhea throughout. This was followed by herceptin and perjeta (Phesgo injection) to complete a full year of treatment. My last dose was one month ago and the diarrhea continues, so I’m guessing that the drugs are still circulating. The itchiness is still very bothersome but may be slightly less intense. I will post when these 2 side efffects are no longer an issue.