Sacituzumab Govitecan (Trodelvy)

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  • denny10
    denny10 Member Posts: 289
    edited September 2022

    I had my scans earlier today. After, a quick unexpected telephone chat, my oncologist gave me the good news , the liver lesions are now responding to Trodelvy, but [why is there always a but!?] I have a clot in my lungs where I have cancer. Tomorrow, I am due to go to an hospital appointment for pre chemo assessment and blood tests and will start treatment to get rid of the clot. I will have a proper consultation on Thursday with the oncologist. I am hoping I will stay on Trodelvy for bit longer.

    Wishing all Trodelvy Travellers well.



  • GR4C1E
    GR4C1E Member Posts: 159
    edited September 2022

    Yikes! (you're right, theres always a big but) Here's hoping that clot will go away! Great news about the liver, though!

    I have my scans tomorrow and follow-up with MO on Friday. I'm hoping for some good news myself - personally I am a fan of the word "stable". Nothing fancy, just no new shenanigans, please!

  • denny10
    denny10 Member Posts: 289
    edited September 2022

    Hi gr4c1e, yes, stable is great as far as I am concerned too. I have a new adventure -injecting myself with blood thinner for the next 2 weeks , then being assessed whether I can change to tablets,[ please! ]. I am having an extra week off Trodelvy as that's probably what's causing the blood problem. Always good and bad news!

    Hope your scans go smoothly and your results are ''stable''.


  • GR4C1E
    GR4C1E Member Posts: 159
    edited September 2022

    OH MY, denny10! Have you ever had to inject yourself before? I'm squeamish when other people do it. Sending good vibes that the blood thinner works it's magic and that nasty clot takes a hike!

    I got my wish. The radiologist used the word "stable" a lot, and even threw in the word "regression" concerning the biggest tumor in my lung - so I'm staying on Trodelvy. My liver has been on the "watch list", due to some interesting polka dots, since March with no changes, so that's good. Ribs # 7 and # 12 remain "chronically fractured" but they've been that way for two years, so no surprises there. The only interesting tidbit was that the pneumonitis that the MO thought was caused by Trodelvy, was misdiagnosed on my 6/15 scans as ground glass nodules and potentially MBC, back when I was still on Abraxane, which was failing and showing progression in all three tumors in my right lung. After two months of Prednisone - the nodules diasappeared and have since been rediagnosed as pneumonitis and are no longer visible on my new scans. (not cancer) AND - turns out, Trodelvy was not to blame, so even better news.

    I have been going for SBRT on my brain tumor since Friday of last week. I'm having three sessions, yesterday was #2 and this Wednesday is #3. So far, no side effects from the radiation except for a bit of fatigue. Then we reassess in 6 to 8 weeks. (MRI)

    Sometimes it feels like metastatic breast cancer is a full time job!

    Think of you. Hang in there. I will if you will!

  • denny10
    denny10 Member Posts: 289
    edited September 2022

    gr4c1e, happy dancing for you, in the circumstances we are in it doesn't get much better. Regression, a word rarely used in connection with MBC. The marks on your lungs being rediagnosed as pneumonitis and dissappearing is great. I hope SBRT hasn't been to hard for you.

    I used to be a blood donor , pre cancer and had to constantly look to the ceiling as I couldn't stand seeing needles in my or others arms, even with numerous blood tests for cancer treatment I could not look. Then covid happened and we were constantly unexpectedly being shown people having vaccinations on TV news and I began to be desensitized. Now I am injecting myself! I get the needle in place and then look away as I plunge it in my skin. The rest is relatively easy. At least another week of injections as I still havent been sent an appointment to anti coagulant clinic. Yes, cancer is a full time job!

    I am with you.



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