Kadcyla for residual disease after neo adjuvant chemo

Noodlesg

Hi Sarah! How are you? I sadly caught covid since the last time I posted. It wasn't really that bad for me, but I am delayed from my next Kadcyla. That worries me more than covid actually, but there is nothing I can do. I dodged covid for sooooo long, it is so frustrating. It takes not being able to get treatment to realize how much you really want it.

On the bright side, my liver values continue to get better. The result from my last blood work was 34 AST (down from 40) 27 ALT (down from 38). My bilirubin also went down from from 15 to 10 (the onco told me she also looks at this number) . So hopefully, I can get my next kadcyla next week.

I went in for a second opinion after my surgery, and the oncologist I spoke to recommended Nerlynx for 1 year. He said there are some unpleasant side effects (diarrhea being the worst), but he said I should do it. My current oncologist hasn't mentioned it to me yet. She is more focused on endocrine therapy at the moment, and just started me on tamoxifen.

I hope #10 goes well for you. Double digits already! Getting closer to the finish line. Way to go.

Did you go get yr hair done? Mine is a bit weird now, I have been going for this pixie cut look, but like yours, the bottom is getting long and it's just all over the place. I just don't want to cut it. I don't know what to do so I do nothing. hahaahah

All the best! Have a great weekend.

Sarah_78

Hi noodlesg,

I had a vacation and feel so relaxed. Now I remember you told me you had a vacation too, this was so much needed. Feel like a new person. Of course vacation and hair dresser I went right before vacation played a role too. He cut my hair in a way that it looks like a hair cut now, not like some hair growing from my head, if you know what I mean. Once that looked half way decent, my self confidence came back because I can go out without putting on a hat and worry about how terrible it looks if I have to take it off. I hope yours grew enough so you can get a hair cut too :-) Much recommended.

I had a check up on Monday, mammo/ultrasound etc, all look normal for now, phew. I have the 11th Kadcyla tomorrow and liver values continue to sink, made it to 62 AST and 42 ALT (down from 71 and 54 respectively). And that when I drank 2 times 1 small glass of wine with dinner and of course once Limoncello which was offer the house I thought I could let it go a little during vacation!

I asked Nerlynx to my onc/gyn who is the director of the breast center and he said that it made no difference in survival rates, it only delays the reoccurrence but if it comes back, it is observed to be more aggressive so one has the same time to live if that happens. So I guess that is a no for me. I read in another (German language) forum that some doctors explained that Nerlynx is also hard on the liver, like Kadcyla so if it reoccurs, it limits your options (Entertu for example is a good drug but it is better if your liver is in a good shape to take it). Try to ask all these questions before deciding on Nerlynx.

Hope you are doing well, how is Tamoxifen? Hope Covid was gentle on you. You resumed your treatment?

Wish you a wonderful weekend too.

Sarah