Small Tubular Cancer - Hormone Treatment?

Susanrun

There is a great article on Treatment of Tubular Carcinoma on the site which subject to the normal caveats provides general guidelines that no hormonal therapy is typically recommended for tubular tumors smaller than 1 cm with no cancer in lymph nodes - my situation.

Oncologists in the hospital that I go to take the position that all HR positive cancers should be treated with hormonal therapy regardless of whether they are tubular, their size or node involvement and won't discuss pros and cons. [Hospital has been great as to surgery and radiation.]

I would like to have a good discussion with an oncologist regarding the issue but not sure how to find one who is knowledgeable in the specific area and will be willing to discuss pros and cons. The article on this site doesn't list authors.

Any help would be greatly appreciated. Thank you!

Susan

Meow13

Interesting, I thought all invasive hormone positive cancers had hormone treatment recommendations. My idc tumor was 1cm and had 25% tubile formations, my mitotic score was 1, so it was a 5 on nottingham score grade 1. No E-cadherin loss. The other 1cm tumor was determined to be ilc based on lack of tubile formation and e-cadherin not present. Apparently my ilc was not typical in characteristics to the thin pattern structure it was tight spherical shape just like the idc.

Also there are very very few idc tumors that have complete e-cadherin loss. I did AI drugs since I was 95% er positive and 0% pr, so pr negative. My hormone therapy was giving only a 1% risk reduction. There some researchers that believe pr negative tumors are not feeding on estrogen and are given high risk oncodx scores. Chemotherapy is recommended even though mitotic scores are 1. Not sure I buy that at all, but cancer is not usually homogenous and is subject to change.