ASCO Recommends Extended Hormonal Tx W/ AIs for HR+ Postmeno

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Updated ASCO Guidelines Recommend Extended Hormonal Therapy With Aromatase Inhibitors for Postmenopausal Women With Hormone-Receptor-Positive Breast Cancer
November 29, 2018
ASCO has updated its guidelines on adjuvant hormonal therapy, recommending postmenopausal women diagnosed with early-stage, node-positive, hormone-receptor-positive breast cancer be treated with hormonal therapy, including an aromatase inhibitor, for 10 years after surgery. Read more...

Ingerp

Ugh. Not exactly thrilled to read this but also not surprised. Thanks for all you do.

Alirena

There is a lot of additional, important information in the original article from the Journal of Clinical Oncology. There is a link to that article in this article.

Murfy

FINALLY, a detailed data and clinical risk stratification for those of us who are N0 and luminal B! Albeit it means 9 more years of AI. Lovely...

april1964

Murfy, where does it mention luminal B?

Murfy

April, if you read the original paper it mentions luminal B in Results section and Discussion. In essence, in luminal Bs and Node+ ladies, 10years of AI is recommended. Luminal A's and low Recurrence Score ladies get a free pass after their 5yrs.

april1964

thank you murfy!!!

Racy

I am happy to continue taking this medication for as long as possible; currently in my eighth year with no side effects.

Castigame

I agree with you Racy. I just passed 1 yr without skipping as well as tolerable SE.

Peregrinelady

What happened to 7 years? Last I heard, they were saying that 7 years was as good as10. It seems like the info. changes every day.

Cowgirl13

I'm wondering too.

Meow13

This is for node positive and hr+ as others have stated.

Cowgirl13

Ok, its the node positive. Got it. Thanks Meow. Fortunately I was node negative.

Peregrinelady

Please remember, though, that a low Oncotype does not necessarily mean low risk after 5 years. My Oncotype was 12; however, my BCI came back with high risk of recurrence.
The article does mention that some people may benefit from 10 years even if they are node negative. I had micromets in one node.

Warrior50

Am I reading this correctly that going to 10 years reduces your risk of BC returning in the same breast of the opposite one but doesn't increase overall survival. If I am reading it, then if you have a bilateral mastectomy would there be any benefit in going beyond the 5 years? I know this is a question for my PO but at my last visit she scheduled a visit for June for a checkup and to discontinue Anastrozole. I just want to be prepared with all the info when we have that visit next year.

I don't mind continuing to take it if there is a reason for it. My worst side affect is hair thinning that maybe would have happened with age anyway.

Peregrinelady

Warrior50, I am wondering what you decided. Are you continuing with the AI?