TN's found to have MpBC

Vjlgrove

Anyone out there thought they had TN only to find out it's Metaplastic Carcinoma? I was initially diagnosed with TNBC in Feb. (tumor was already > 5 cm) and began chemo in March hoping for a lumpectomy. When my tumor didn't respond to either AC (3 doses) or CT (1 and 2/3 doses) we moved forward with surgery. Pathology of the tumor showed MpBC with osteosarcomatous differentiation (unresponsive to chemotherapy). I'd had a normal mammogram in 07/2017, have no real family history, and the lump showed up overnight and was painful - neither of which I thought cancers usually were - and I'm a nurse!

I now have 4 nodules in the right lung and have had a recurrence in the chest wall along the surgical incision (that recurred overnight again 3 1/2 weeks after my surgery).

This cancer is just moving so fast. I'm following the MD's advise, have incorporated some nautropathic therapies (IV Vitamin C, diet modification - although not enough to make the NMD happy, and meds/dietary supplements (Metformin and low dose Naltrexone, and multiple other supplements - one of which (Pectin something) actually made me vomit which didn't even happen on chemo!). Genomic sequencing is back but there are 13 mutations. Hoping there's an effective immunotherapy but worried if I get one, another of the mutations will go unchecked!

Any thoughts or recommendations.

Parrynd1

Vjlgrove, how did they find out it wasn't just TN? Your story sounds scary familiar to mine. When I first found my first lump it was because I was having pain. AC was a joke and did almost nothing, had surgery, TC they think failed (done after surgery due to positive lymph node), and breast tumors recurred during radiation. I had a meningeal brain met and have multiple lung nodules. Both of my grandmothers had BC, but not TNBC. I don't haven the common gene mutations. We did extended gene testing and I have 4 mutations they don't know anything about other than they are mutations. I have had many biopsies (mostly from the clinical trials I’ve tried) and haven’t had the results change. I’m hoping this is a good thing. To think I’ve spent the last few years fighting the wrong cancer would be devastating.