6mm IDC Grade 2 ER- HER2+ 1/3 nodes - Advice please!

JRC46

Hello

I am posting on behalf of my mother to try and find out some more information for her to help determine next steps.

She is late 50's and was initially diagnosed with DCIS 6 months ago, from some calcium deposits on a routine mammogram. She had two local excision's which were unsuccessful.

The supporting report showed 6mm invasive ductal carcinoma, grade 2, ER negative, HER2 positive.

She has recently had a mastectomy with immediate reconstruction, but is now being told that Herceptin and Chemotherapy are recommended next steps.

I guess my questions are:

- Firstly, can anyone relate with a similar timeline of events/diagnosis?

- Are Herceptin/Chemotherapy the usual route with HER2+ at this stage, regardless of the 1/3 node and 6mm?

- Is the prognosis good? I'm trying to find some positives to take from this as from the initial DCIS diagnosis it seems to have got a lot more serious very quickly!

Also, if someone is able to explain the ER negative to me, and how this impacts/changes anything by being negative rather than positive, that would be great.

Many thanks in advance

J

Beatmon

Her2+ is very aggressive so that is why the recommendations for the big treatment. Herceptin has changed the game since it was found and makes the her2 treatable. Many of the bad statistics you see are old. There is a video called Living Proof which is about how it was invented. Best of luck to your mom