Inherited epigenetic changes can also cause bc

besa

https://www.nature.com/articles/s41467-018-03058-6

https://medicalxpress.com/news/2018-02-familial-br...

"The study, published in Nature Communications, looks at epigenetic changes called DNA methylation, where methyl group chemicals modify DNA without changing its sequence. DNA methylation can mimic genetic variation, predisposing a family to breast cancer. The study is one of the first to systematically scan the genome for places where DNA methylation is heritable, and is the first to apply this to familial breast cancer."