New meds

neogirl

Hi,

I am have been on tamoxifen for many years and after that stopped working I was put on arimidex. Well I think that has not stopped working now. Anybody know what drug is next in the pipeline after these 2 stop working. Just curious. Kinda worried.

50sgirl

Hi Neogirl, I was on Arimidex as my first line treatment. When that failed, I was put on Faslodex ( monthly injections) and Ibrance ( pills, 21 days on, 7 days off cycle). (Tamoxifen will likely be my next step.) I have been on Faslodex and Ibrance for more than a year and a half and am doing well. I find it to be a very easy treatment. Ibrance does cause a drop in blood counts, most notably WBC and neutrophils. If they drop too low, a reduced dose is given. I only lasted on 125 mg for one month and have been on 100 mg since then. Many people suffer some degree of fatigue from Ibrance, but I have not.

There are other choices out there, too. Let us know what develops.

Hugs and prayers from, Lynne

ABeautifulSunset

Lynn is right. Ibrance and Faslodex are likely next. Combining drugs are the thing right now.

There is also xeloda down the pipeline,

Still lots of stuff for you. Keep positive.

Sunset

pajim

Agreed. Faslodex, with or without Ibrance. Not hard to take. Ibrance is a little harder. Fas will be a lot like Arimidex, except for the pain in the ass.

Do you have Bestbird's guide? You should request it. There's a pinned thread about it. She has all the treatments laid out as first, second, third line therapy. Really helpful when you're considering options.

neogirl

Thank you all for the info. I really appreciate you all.

Pajim- I didn't even know about Bestbird's guide. I just requested it. I look forward to getting it and hopefully will answer lots of questions coming up in the future.