TC or CMF

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cincydeb
cincydeb Member Posts: 2

I'm not sure which chemo option to choose TC or CMF but I was told they are both equally effective. TC would be 6 times every three weeks with complete hair loss and CMF would be 9 times every three weeks with thinning hair. Any advice would be appreciated.

On January 10th, I had a lumpectomy on left side, 1 centimeter, Stage 1a, ER/PR +, HER2-, but unusually high onco score of 27

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  • Meow13
    Meow13 Member Posts: 4,859
    edited February 2018

    debbie, 27 is an intermediate score, I had a 34 but I chose no chemo and did AI drugs. I was recommended AC & T by mo, he said I could try CMF. I didn't want the risk associated with chemo and certainly didn't want the hair loss. However, I had no idea cold caps and other meds could be used to make chemo more acceptable to me.

  • Jackster51
    Jackster51 Member Posts: 357
    edited February 2018

    I would go CMF if I had a 'do-over'. I did NOT get my hair back after Taxotere, that was 6 years ago. I also still have crippling neuorapathy in my feet. I was 46 at DX, so both of these permanent side effects from Taxotere have altered my life a lot! I have heard much better things about CMF, so if you are given the chance, I'd go that route. Just my 2 cents!

  • Shell07
    Shell07 Member Posts: 10
    edited February 2018

    I am in your shoes! Oncotype 33. My local hospital only offered me TC but went for 2nd opinion at Sloan Kettering CMF was their suggestion. I start CMF February 27th every 2 weeks at my local hospital.

  • OCDAmy
    OCDAmy Member Posts: 873
    edited February 2018

    I did four rounds of TC and tolerated it very well and my hair is coming back.

  • cincydeb
    cincydeb Member Posts: 2
    edited February 2018

    I am leaning towards CMF but getting a second opinion. Thanks for providing your experience.


  • Meow13
    Meow13 Member Posts: 4,859
    edited February 2018

    Debbie, the way it was put to me was ACT would be a 3 month deal and CMF would be 6 months. My mo said I would think you would want 3 months but told me my risk reduction would be the same on CMF. I felt extreme pressure to decide immediately and I chose just AI therapy. But honestly they totally down played any permanent side effects of the treatment. I feel like my body aged 10 years on my bones and joints. So glad to off drugs.

  • mustlovepoodles
    mustlovepoodles Member Posts: 2,825
    edited February 2018

    i had 4 rounds of TC. Other than the usual side effects--fatigue, taste changes, diarrhea, hair loss--i did fairly well. Afterward, my hair came back, the diarrhea went away, the fatigue vanished, and the taste buds returned to normal. My Onco score was 23--intermediate--but my tumor was PR-, a somewhat more aggressive type. I did not regret having chemo. The only long-term side effect I had was poor concentration--chemo brain--, but even that has improved.

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