Anyone on AIPac with Paclitaxel plus LAG-3Ig ?

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NettaGER
NettaGER Member Posts: 134
edited February 2018 in Stage IV/Metastatic Breast Cancer ONLY

Does anyone have experience with the AIPac trial consisting of Paclitaxel and LAG-3Ig, the latter also called IMP321? Does it work? How are the side effects?

I could qualify for the clinical study NCT0261483, being ER/PR+ and not having had a chemo yet.

However, I am somewhat concerned, because the placebo arm contains Paclitaxel only on day 1, 8 and 15 of each 28 day cycle. As far as I know, the normal regimen as per standard of care would be weekly Paclitaxel without a week off, right? And how many cycles of weekly Paclitaxel would be normal, 6 cycles or until progression/non-tolerable side effects?

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