Single receptor status E rich

SueRobbo

Am wondering if single receptor status makes a difference to treatment and long term outcomes because I have had so much confusing information.Aged 66, diagnosed 11/12/2017 after mammogram, ultrasound and biopsy. Invasive Ductal Carcinoma. Grade 3. Single hormone receptor positive, ER 8/8, PGR 0/8. HER2-. Had wire guided WLE and sentinel node operation 21st December and awaiting review and treatment options.

SavedbyGrace1972

SueRobbo

I sure do wish I knew the answer to your question. As far as I know, ER+ and PR+ respond well to hormone treatments. Good luck to you. 

SueRobbo

Thank you. Nervously awaiting my treatment options!

SueRobbo

Perhaps Ribociclib will be made available in Wales for Er+, HER2- IDC

SavedbyGrace1972

I too am ER+ PR- and HER2 - and was wondering about treatment options.

Anna-33

I am only Estrogenpositive. My treatment is 4 AC and 12 Taxol, radiation and tamoxifen. What kind of treatment do you get?

SueRobbo

Anna I had my post operative meeting with my surgeon yesterday. My Grade 3 IDC has been mysteriously downgraded to Grade 2 although the tumour has been upsized from 20mm to 24mm. I have a copy of my doctors letter which confirms the Grade 3 however. I’m still Er+ (100%) and other receptor negative. I was flabbergasted to be told that I would only need AI to suppress the estrogen. No chemo or radiotherapy. I thought adjuvant radiotherapy was a gold standard for single receptor status lumpectomies ( had I know I would have requested a mastectomy) however my surgeon quoted a 2008 study be Kyndi Et, al., (that was inconclusive due to datasets) that says wome over the age of 60 with Luminal A type cancers (ours I understand) do not benefit from adjuvant radiotherapy. I checked on Predict and Adjuvant and my survival would be improved 5% with chemotherapy but I am not even being considered. I amquietly seething and putting it down to cost cutting.