Taking a Break From Letrozole Therapy After Breast Cancer

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voraciousreader
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“SOLE was published online November 17 in Lancet Oncology.

The investigators, led by Marco Colleoni, MD, from the International Breast Cancer Study Group in Milan, Italy, conclude that the study results on "intermittent administration [of letrozole] provides clinically relevant information about extended adjuvant endocrine therapy with letrozole and support the safety of this option for temporary treatment breaks in select patients who may require them."

SOLE can be regarded as a "planned nonadherence study," say V Craig Jordan, OBE, PhD, DSc, and Balkees Abderrahman MD, from the department of breast cancer oncology at the University of Texas MD Anderson Cancer Center, Houston.”


https://www.medscape.com/viewarticle/889157

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