Breaking Research News from sources other than Breastcancer.org

Chemokaze

Top oncologist to study effect of diet on cancer drugs:

http://flip.it/1Dcoeh

aterry

Lumpie, The Medscape article about Starbucks coffee is so interesting. I just recently became aware of the California warning (late to the game, I guess) and now I'm seeing it all over the place. I just returned a lawn sprinkler to Ace hardware (to corporate, not the store) because it has the warning. I'm guessing there are many, many items with the warning. Now that I know to look I'll probably see it everywhere.

marijen

aterry, wait! What? A lawn sprinkler may cause cancer!?

Anonymous

marijen, my reaction exactly. Whaaatttt?

Although here in Arizona, because we are in terrible drought, we don't water anything much anyway.

And where was this Starbucks article (Lumpie)? Did I miss it somewhere?

aterry

Marijen, There is a warning on some products that I refer to as the California warning. It's not new but I just recently became aware of it. I was buying car cleaning stuff and one item I looked at (didn't buy) had a big yellow warning "This product was manufactured using one or more chemicals known to the State of California to cause cancer and or birth defects. Wash hands after using." Since then I've been looking to see where else the warning pops up. I bought a new lawn sprinkler at Ace hardware (DoItBest) and didn't see the tiny warning until I got home and was reading the set up instructions. I was mad at myself for buying it. I packed it up and mailed it back to the company with a letter; I didn't want to return it to the store to be purchased by some other person. I'm sure the manufacturer will say that the risk is minimal, but....... Now I use a 30-year-old sprinkler that is made from cast iron.

Mostly I'm bummed because it's clear that many, many things that are in our daily orbit are questionable. I'm sure it's not possible to avoid them all and even making informed choices is confusing.

Here's a piece from the American Cancer Society about the warning: https://bit.ly/2ldsDg9

marijen

Aterry, thanks for the clarification. I wonder if the sprinkler was made in China. I think it’s great we are getting warnings. Especially if on kitchen utensils and toys. I don’t live in CA. If they keep up these warnings maybe manufacturers will get the message. I agree we are exposed to too much toxins in our environment. And now the animals are going extinct because of the way we are degrading the planet. Smog is my pet peeve. I just want clean air and clean water to start. Not adulterated water. Not filthy air. We are all entitled to that at the least.

Anonymous

Ah, I get it now. Arizona has no such warning, but I do know about the hazards of paper receipts from stores (grocery etc) and wash my hands to remove the chems that can cause cancer from those receipts. Whole Foods, I know, uses paper that is safe, but others don't.

Claire

aterry

Marijen & Claireinaz, the warning exists on products all over the country. I live in NYC. I call it the California warning because it relates to legislation passed in that state and because the warning specifically says, "...known to the state of California to cause cancer and/or birth defects...." The guy at the hardware store said to me, "You don't have to worry about it since this isn't California." I said, "Do you think cancer knows what state you live in?" A neighbor found the warning on a portfolio that she bought for her art work. I think it's widespread.

And, yes, the products I saw were made in China but I don't know whether manufacturers in the US have eliminated those chemicals from their supply chain.

marijen

aterry, great answer. What did the hardware guy say to that

Chemokaze

Oncolytics: Significant Pipeline Value In The Fastest Growing Area Of Oncology

http://flip.it/IeTS-A

marijen

Who are 'You People' Anyway? – National Pain Report

http://nationalpainreport.com/who-are-you-people-a...

marijen

APPROVED FOR TREATMENT AFTER SURGERY FOR 1 FULL YEAR (UP TO
18 CYCLES)

PERJETA® (pertuzumab) is approved in combination with
Herceptin® (trastuzumab) and chemotherapy for patients with
HER2+ early breast cancer that has a high likelihood of coming back.

https://www.perjeta.com/patient.html

Is this old news? It came in my mail today.

illimae

marijen, I think the new part is the additional of Perjeta in early stage treatment. As stage IV HER2+, this combo is standard protocol.

MinusTwo

I agree. I know some women who had H&P along with neo-adjuvant chemo but still had to fight to get their insurance to pay for Perjeta the rest of the year after surgery.

marijen

Oh good, then I'm glad I posted it. Thanks Illimae and MinusTwo. It says 18% more chance of recurrence for HER+

illimae

yeah, 18% is not good. HER2 also likes the brain as I and many have discovered. Oh well, we do what we can.

Thanks for posting all, I read this often but don’t add much.

aterry

Chemokaze, thanks for posting the Siddhartha Mukherjee article. Many times when people learn that I've just been treated for cancer they tell me about anti-cancer diets they've heard about. They are always very intense about these diets and are frustrated if I don't immediately embrace the diet. During my treatment I relied on the nutritionist at the Dubin Breast Center when I wasn't sure how to plan. I think it's great that there will be actual data about a specific approach.

mike3121

Something I came across:

https://medicalxpress.com/news/2018-07-scientists-sharpen-edges-cancer-chemotherapy.html

My wife is now on Halaven as her Xeloda failed her. She's tolerating it okay. Her ER/PR+ turned triple negative about 1 1/2 years ago and was put on Xeloda.

Pi-Xi

Comparison of Treatment Outcomes with Breast-conserving Surgery plus Radiotherapy versus Mastectomy in Patients with Stage I Breast cancer: A Propensity Score-matched Analysis

Not that I had a choice in my surgery, but this wasn't a great abstract for me to see first thing in the morning. Good news for others though.

marijen

CDC Opioid Restrictions Reading List | EDS and Chronic Pain News & Info - long list of links here

https://edsinfo.wordpress.com/pain/cdc-opioid-restrictions-reading-list/

marijen

Get Ready for the Future!

Trackable Pill Technology and Smart Bottles

6 Replies

https://edsinfo.wordpress.com/2018/07/11/trackable...

Chemokaze

Fighting Cancer With Cancer: Scientists Use CRISPR To Tweak Tumor Cells And Make Them Attack 'Their Own Kind'

http://flip.it/hq2KKN

(This article includes METASTATIC BREAST CANCER

marijen

That’s funny! I hope it works

Lumpie

Potential DNA damage from CRISPR has been 'seriously underestimated,' study finds

https://www.statnews.com/2018/07/16/crispr-potenti...

Research published on Monday (16 July 2018) suggests that... CRISPR-Cas9 can cause significantly greater genetic havoc than experts thought... perhaps enough to threaten the health of patients who would one day receive CRISPR-based therapy.... Some CRISPR'd cells might be missing a key anti-cancer mechanism ....

Lumpie

Curing Metastatic Breast Cancer

http://ascopubs.org/doi/full/10.1200/JOP.2015.0089...

Metastatic breast cancer is generally considered incurable, and this colors doctor-patient interactions for patients with metastatic disease. Although true for most patients, there appear to be important exceptions, instances where long-term disease-free survival occurs. Although these instances are few in number, they suggest the possibility of cure. How will we move toward cure for a much larger population of patients with metastatic disease? This article outlines a potential research agenda that might move us toward that distant goal.

{article is from 2016 but interesting}

marijen

A very interesting, honest and sobering article Lumpie, thanks for posting. Just as I suspected.

MinusTwo

Wow Lumpie. Yes, thanks for posting. Since I had what was called a 'recurrence' after BMX, and the type 'mutated' from DCIS to IDC - this article makes sense of a lot of loose ends.

Heidihill

Lumpie, thanks for the link. I am a long-term survivor of mets at almost 11 years out. Just eyeballing those stats I will likely make it to 15, even 20.

"Studies of tumor-infiltrating lymphocytes in the adjuvant setting have suggested that their presence is a powerful predictor of outcome, suggesting that we already rely on the immune system for therapeutic impact even in the absence of immune-based therapies.^26"

This has been the only explanation that made sense to me, although I don't really know if my tumor had a lot of TILs. Given the outcome, it probably did.

I had neoadjuvant chemo, surgery, radiation and hormonal treatment.

I put my hopes on this article from 2001 when I started treatment in 2007, Can We Cure Limited Metastatic Breast Cancer? The odds were much lower then.

http://ascopubs.org/doi/full/10.1200/JCO.2002.20.3.620

marijen

Heidihill, that’s great for you! May I ask why you didn’t start Tamoxifen until 2015?

marijen

FDA Expands Ribociclib Breast Cancer Approval Under New Pilot Programs

https://onclive.cmail19.com/t/j-l-ntujruk-jrtrfkdyh-y/