My sister's diagnosis + Spindle Cell Metaplasia??

TSeaboy

Hi everyone,

My 39 year old sister was diagnosed with stage 4 breast cancer around 2 months ago. I'm not very medical term inclined, but we know this:

There are actually 6 masses in her left breast. Five are contained within the breast, one is "intimately associated with the chest wall".

There is cancer in one of the axillary lymph nodes on the left side.

There is cancer in the internal mammary lymph node chain.

There is a 3.2cm x 2.2cm tumor in her liver.

The MRI of her liver confirmed the metastatic lesion.

Final diagnosis is Stage 4, metastatic breast cancer with high grade spindle cell metaplasia.

What, exactly, is spindle cell metaplasia?

She also had genetic testing done and those results came back negative.

She's currently involved in this clinical trial:

"Randomized Phase III study of pembrolizumab plus chemotherapy vs placebo plus chemotherapy for previously untreated metastatic triple negative breast cancer."

Chemotherapy = Abraxane.

Does anyone have knowledge? Experience?

beach2beach

I am sorry to hear of your Sister's diagnosis. I don't have any information on it, but glad you are on here and asking and looking. I hope things work out for her.

I'm sure someone will pop on here who will have some information. I would say, if you have not already, post in the Stage IV thread. sure there are women who can answer many questions you may have.

MTwoman

TSeaboy, I am also so very sorry about your sister. Here is a link that can better explain her type of bc: http://breast-cancer.ca/spin-cell/

I am certain others will come along soon and help with your other questions.

Sending you and your lovely sister warm wishes and ((hugs))