Good news for bc men, the survival gap narrowing

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Traveltext
Traveltext Member Posts: 2,089
edited November 2017 in Male Breast Cancer

Although overall survival of men with breast cancer lags behind that of women, the gap is narrowing.

CHICAGO June 5, 2017 — Male breast cancer patients are less likely than their female counterparts to receive adjuvant hormone therapy, according to study findings presented at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting.

In addition, compared with women, men who undergo lumpectomy are less likely to receive adjuvant radiation.

Using the National Cancer Data Base, researchers led by Esther Dubrovsky, MD, of The Perlmutter Cancer Center at NYU Langone Medical Center in New York City, identified 2,047,868 patients with breast cancer diagnosed from 2004 to 2014. Of these, 19,409 (1%) were men. Dr Dubrovsky and her colleagues divided the male cohort into an earlier group (2004 to 2009) and a later group (2010 to 2014). The groups included 9790 and 9619 men, respectively.

Compared with the earlier group, the later group underwent fewer lumpectomies (24% vs 27%, P <.0001), but were more likely to receive postlumpectomy radiation (68% vs 61%; P <.0001). The proportion of men receiving adjuvant hormone therapy was significantly higher in the later than earlier group (61% vs 49%; P <.0001).

Compared with women, men were older and had a slightly later stage at diagnosis and larger tumors. Male patients with breast cancer had higher rates of ER-positive and PR-positive tumors than women (91% vs 80% and 82% vs 69%, respectively; P <.0001), but lower rates of adjuvant hormone therapy (55% vs 58%; P <.0001). A smaller proportion of men than women receive postlumpectomy radiation therapy (16% vs 44%; P <.0001).

Although overall survival (OS) of men with breast cancer lags behind that of women, the gap is narrowing. For men and women whose cancer was diagnosed during 2004 to 2009, overall survival was 66% and 77%, respectively (median follow-up 73.9 months vs 80.4 months). For men and women whose cancer was diagnosed during 2010 to 2014, OS was 84% and 90%, respectively (median follow-up 33.85 months vs 35.91 months).

Comments

  • Traveltext
    Traveltext Member Posts: 2,089
    edited June 2017

    KB870, men rarely, if ever, are given a lumpectomy because of their small amount of breast tissue. Mastectomies are standard practice so as to remove all the tissue for clear margins. So, Brachytherapy would be an unlikely option to replace rads. It's great that you could have this treatment which I can see you have recently completed.


  • Jcempire
    Jcempire Member Posts: 6
    edited November 2017

    The real stats are us, everyone is different and so is the type and response to treatment.

    18 1/2 years and I'm still going very strong which proves men can survive for a long time too.


  • Traveltext
    Traveltext Member Posts: 2,089
    edited November 2017


    Congratulations Jcempire. Indeed men can survive this dreadful disease for a long time.

    And, like you, we can be diagnosed Stage IV any time. All the best with your ongoing treatment.


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