No recurrences after pcr?

Desirr77

I am wondering if there are any recurrences after patholog complete response? Are there any stats to read? I am reading of an excellent prognosis for those wth pcr and almost 0 recurrences. Can you confirm that by your own experience?

Thank you!

MinusTwo

I did not have pCR from the first 6 rounds of neo-adjuvant chemo after my recurrence. So after the surgery that followed, I had 4 rounds of a different chemo. Then rads. And Herceptin for a year.

So it's my experience that there are further treatments if you don't achieve pCR the first time out of the box. I've been NED now since final treatments 2-1/2 years ago. I've had regular MRIs or CTs or PET/CTs to confirm this.

Sam0623

I'm no expert, but everything I have read says the chance of reoccurance after a PCR for TNBC is about 10%. I talked to a nurse about a clinical trial for women without a PCR last week and asked her if she knew about any trials for women that get a PCR and she said no, that the lead oncologist believes 90% of women who get a PCR are cured.

Desirr77

In Germany there is a famous table from 2008 that says 94% of TN with pcr are alive after 7 years. 6% recur within the first 2 years. I am wondering if this is the same in the US. And i would like to know if there are women with recurrance after pcr here in this forum.

TulipsAndDaffodils

10% is what my MO told me and what I've read. I've seen some people on the forums recur after pCR, but it is obviously not a common situation (since only about 20% get a pCR and then only 10% of those people recur...so only 2% of TNBC patients are those with both pCR & recurrence). Overall, it's a very encouraging prognosis!

wrenn

I have a (likely) stupid question. What is the difference between PCR and NED?

NotVeryBrave

I believe PCR (pathological complete response) is no cancer seen after neoadjuvant chemo and NED (no evidence of disease) is no cancer seen after all treatment is finished.

MinusTwo

NotVery is correct.