Pleomorphic Lobular Carcinoma

123abc1611

Could I hear some survivor/progression stories from those of you diagnosed with "pleomorphic lobular carcinoma"?

Below is part of what my pathology report from biopsy says. I am scheduled for MRI of breast on Friday and consult with surgeon. ER+\PR+. My HER2 came back unequivocal so I'm waiting for FISH test, I am a 19 year survivor of breast cancer. This is a new primary and not recurrence. Mass is approx, 1.75 cm and in 2 o'clock position in left breast at exact same position as earlier tumor which was removed via lumpectomy.

"Microscopic description is invasive carcinoma is present in all three tissue cores with a maximum linear extent of 1.7 cm. The tumor exhibits no lubule formation, moderate nuclear atypia and a low mitolic rate, for a combined Nottingham grade II. No in-situ carcinoma or lymphatic vascular space invasion is identified. Much of the tumor exhibits plasmacytoid morphology, suggestive of pleomorphic lobular carcinoma. An immunohistochemical stain for E-cadherin is negative, supporting this classification.

ER (clone 6F11): Positive (30% weak, with focal "hot spot" that is 80%, intermediate)

PR (clone 16); positive (95% strong)

KI-67 (clong MIB-1): approximately 10%"

Thanks in advance. I have almost made my mind up to go with a double mastectomy if this will increase my odds of longer survival. I'm 63 and really don't need those boobs for anything at this point in my life anyhow.

ner48

I am sincerely sorry for what you are going through.

I was just diagnosed on a mammogram with Pleomorphic microcalcifications clusters and have an appointment with a surgeon for a consult for a stereotactic biopsy in a couple of days. I have a very strong family history of breast cancer with my Mom, Sister (last year) and 2 maternal aunts. I have extreme anxiety and panic and do not think that I can lay on that table for such a long amount of time without moving.

I completely understand when you say a double mastectomy because my aunt went through the same thing and made the decision for the mastectomy. She is a 5 year survivor and is 75 years old. I am almost 68 and feel that if they do find something I do not want to play the wait and see game every year to see if it has come back. I certainly do not want to take the chance of it spreading elsewhere.

My thoughts and prayers will be with you as you make this decision. I feel that you and only you know your body and know what is best.

God Bless