List of trails for HER2+ ER-/PR- metastatic BC

fight2s

I have collected some of the clinical trails which are specific to metastatic HER2+ ER-/PR- subtype. Thought this may be of help to others as well. Do add if I missed any.

Phase 3

Neratinib Plus Capecitabine https://clinicaltrials.gov/ct2/show/study/NCT01808...

Phase 2
Targeted
Lapatinib, Everolimus and Capecitabine https://clinicaltrials.gov/ct2/show/NCT01783756
Poziotinib https://clinicaltrials.gov/ct2/show/NCT02659514
ONT-380 with Capecitabine & Trastuzumab https://clinicaltrials.gov/ct2/show/study/NCT02614...
Everolimus, Trastuzumab And Vinorelbine https://clinicaltrials.gov/ct2/show/NCT01305941
Ribociclib with TDM1 https://clinicaltrials.gov/ct2/show/NCT02657343
Neratinib https://clinicaltrials.gov/ct2/show/study/NCT01953...
Palbociclib with TDM1 https://clinicaltrials.gov/ct2/show/NCT01976169
Enzalutamide With Trastuzumab https://clinicaltrials.gov/ct2/show/study/NCT02091...
Eribulin Mesylate, Trastuzumab, and Pertuzumab https://clinicaltrials.gov/ct2/show/NCT01912963
Gemcitabine, Trastuzumab, and Pertuzumab https://clinicaltrials.gov/ct2/show/NCT02252887
https://clinicaltrials.gov/ct2/show/NCT02139358
Cabozantinib With Trastuzumab https://clinicaltrials.gov/ct2/show/NCT02260531
PD 0332991 https://clinicaltrials.gov/ct2/show/NCT01037790
PIK3CA
Albumin-Bound Rapamycin https://clinicaltrials.gov/ct2/show/NCT02646319
BGJ398/BYL719 https://clinicaltrials.gov/ct2/show/NCT01928459
https://clinicaltrials.gov/ct2/show/NCT02038010
LJM716, BYL719 and Trastuzumab https://clinicaltrials.gov/ct2/show/NCT02167854
PM01183 https://clinicaltrials.gov/ct2/show/NCT01525589
Taselisib https://clinicaltrials.gov/ct2/show/NCT02390427
Immunotherapy
Pembrolizumab + TDM1 https://clinicaltrials.gov/ct2/show/NCT02318901

Phase 1
PIK3CA
Temsirolimus With Metformin https://clinicaltrials.gov/ct2/show/NCT01529593
BKM120 or BYL719 https://clinicaltrials.gov/ct2/show/study/NCT01300...
AZD5363 https://clinicaltrials.gov/ct2/show/NCT01226316
Targeted
Ruxolitinib With Trastuzumab https://clinicaltrials.gov/ct2/show/NCT02066532
TDM1 With Abraxane and Lapatinib https://clinicaltrials.gov/ct2/show/NCT02073916
T-DM1 With Neratinib https://clinicaltrials.gov/ct2/show/NCT02236000
Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab https://clinicaltrials.gov/ct2/show/NCT02060253
Pyrotinib https://clinicaltrials.gov/ct2/show/NCT02500199 FS102https://clinicaltrials.gov/ct2/show/NCT02286219
Vorinostat With Paclitaxel and Carboplatin https://clinicaltrials.gov/ct2/show/NCT01249443 MEDI4276https://clinicaltrials.gov/ct2/show/NCT02576548 https://clinicaltrials.gov/ct2/show/NCT01421524BAY1125976 https://clinicaltrials.gov/ct2/show/NCT01915576
Ribocilcib (LEE011) https://clinicaltrials.gov/ct2/show/NCT02599363
Immunotherapy
Autologous Dendritic Cells Loaded With Oncofetal Antigen/iLRPhttps://clinicaltrials.gov/ct2/show/NCT00715832 https://clinicaltrials.gov/ct2/show/NCT02479230https://clinicaltrials.gov/ct2/show/NCT01376505 https://clinicaltrials.gov/ct2/show/NCT02048709
TAA-Specific CTLS https://clinicaltrials.gov/ct2/show/NCT02239861https://clinicaltrials.gov/ct2/show/NCT02276300
AVX901 https://clinicaltrials.gov/ct2/show/NCT01526473

lovelylibra

Thank you! This helps!