First large-scale proteogenomic BC study
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cp418
Member Posts: 7,079
https://www.sciencedaily.com/releases/2016/05/1605...
First large-scale proteogenomic study of breast cancer provides insight into potential therapeutic targets
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It's about time this research was done. Thanks for posting this cp418. I meant to post it yesterday, but been so damn busy. This does seem important since Genomics (DNA mutations) are only part of the problem with cancer.
Published: 25 May 2016
Media news: www.bcm.edu/news/cancer-breast/proteogenomic-breas...
First large-scale proteogenomic study of breast cancer provides insight into potential therapeutic targets
Science version of the news: www.nature.com/nature/journal/vaop/ncurrent/full/n...
Proteogenomics connects somatic mutations to signalling in breast cancer.
Some quick thoughts / questions:
1. How many of the ~77 breast cancer samples were the Lobular subtype?
2. Can any of these new insights be exploited by the numerous emerging Immunotherapies or is this only relevant to Kinase inhibitors?
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