ipsilateral recurrence of triple negative .4 mm TX options?

MKCROWE

Hi there,

I have had a recurrence 4 years since my original diagnosis. Mammography suggests .4 mm. It's small. No knowledge yet of node involvement. I was originally stage II no lymph node involvement. I get a mastectomy next week. I am not BRCA 1 or 2, although there are some good therapies emerging for that group. Anyone have an idea of neoadjuvant targeted treatments or therapies I should consider before doing surgery? Or after surgery? Anyone done radiation twice? ACT twice? I know they can't do ACT a second time for risk of heart failure, and it didn't fully treat the cancer the first time, but if I am bound for mets anyway, I don't see why not.

Thoughts?

OR anyone out there had a recurrence like this that can offer hope?

Thank you!

Moderators

We are really sorry you find yourself going through this again! We're all here to help you. You may want to take a look at the following article on our site: How Triple-Negative Breast Cancer Behaves and Looks. There are options out there. We will be thinking about you next week with your surgery. Please keep us posted.

slv58

Hi MKCROWE, I'm sorry you find yourself here. I had a local recurrence 17 months has after completing chemo, LX and rads. I did achieve PCR - or so pathology thought. I had FEC-D the first time and was not a candidate for it again as it was explained to me that technically it didn't work the first time if I had a recurrence so soon. My MO said there was newer studies showing a platinum chemo had beneficial results for TN, even without being BRCA positive. I had a MX with immediate diep, then started cisplatin and gemcitabine. There was a debate as to whether I would have rads a second time but it was decided that it was too soon after completing the first time. This surprised me as I didn't think I could have rads again, but apparently you can.

I am 7 months out from completing chemo and honestly feel great! All my joint pain that I've had since my first chemo is 75% better. I wish you the best, it is doable!