Lowered dosing of chemo to stop tumor growth

Unconventional treatment strategy controls -- rather than eradicates -- cancer

"The researchers tested the approach with the chemotherapy drug paclitaxel in mice with two different types of breast cancer. Standard chemotherapy shrunk the mouse breast tumors, but only to have them grow back as soon as treatment stopped. Another treatment regimen that skips doses whenever the tumor shrunk also inevitably resulted in tumor progression.

In contrast, adaptive therapy consisting of high initial drug doses followed by progressively lower doses as the tumor responded was more effective in controlling tumor growth than either standard therapy or dose skipping.

In fact, the treatment allowed between 60 and 80% of the mice to be weaned off the drug completely without relapsing for an extended period of time."


https://www.sciencedaily.com/releases/2016/02/1602...

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