BRIP1 gene mutation -ovarian cancer risk quantified

besa

http://medicalxpress.com/news/2016-01-quantifies-f...

http://www.sciencedaily.com/releases/2016/01/16011...

"Women who carry an inherited fault in the BRIP1 gene are three times more likely to develop ovarian cancer than those without it, researchers said Tuesday.

The gene variant had already been linked to cancer of the ovaries, but the size of the additional risk has now been quantified in a study in the Journal of the National Cancer Institute.

Around 18 women in every 1,000 develop ovarian cancer, but this risk increases to around 58 women in every 1,000 for women with a fault in the BRIP1 gene," said a statement from Cancer Research UK, whose researchers led the research...."

"They found that women who carried the BRIP1 mutation were more likely to be diagnosed with an aggressive form of cancer, at a later stage and at an older age."