Oncotype 51, ER- PR+ HER2- treated like Triple Negative BC?

Citrinetiff

Hi,

I was told this morning that my Oncotype score is 51, and my hormone status (ER- PR+ HER2- suggests that I'm closer to triple negative BC. Oncologist suggests 4 cycles of AC every three weeks (3 months) and then Taxol every week for 2 months. Anyone have similar dx? Can anyone please give me some info and reassure me that the regimen is doable? I'm feeling completely overwhelmed.

Cathytoo

I am definitely Triple Negative. I saw three oncologists. One through everything in the book at me including Carboplatin. Passed him by. Second oncologist suggested AC+T providing an echo cardigan was normal. He said the A had a 2% change of resulting heart issues. Third oncologist said their team was throwing out the A because of the many resulting problems. He suggested 4 rounds of TC...an additional 2 if I am doing well with few side effects. I chose #3 oncologist and start my chemo tomorrow. I am well aware that AC+T has been the gold standard for Triple Z Negative. But, I've been doing a lot of research since my diagnosis. Everything about triple negative is unknown at this point in time. Some hospitals are using CMF, which is "old time" chemo. As far as AC+T, I know several Triple Negatve women who are here to tell their story...many years later. I hope I made the right choice. Tonight I'm hoping I did the right thing declining the more aggressive Treatment. I'm a very healthy 76 year old woman. I don't take one pill for anything. My oncologist said we are doing the maximum treatment with the minimum damage. It's a very personal decision. Best wishes to you

Citrinetiff

Cathytoo,

Thank you so much for your response. It is so difficult to make the decisions we need to make. My doctor feels that since I am 52, am Grade 3, and have an Oncotype of 51, we should follow this treatment.

We can't, or perhaps shouldn't, think about the what-ifs. I don't know if this regime is too aggressive, but it's what I decided to do with the info I have. and you have done the same. We just have to go through it and get to the other side.

Again, thank you, Cathytoo.

Cathytoo

Citrinetiff...I agree with you 100%. We have to have confidence in our doctor and our gut feeling. I believe there is a higher power somewhere who has the answers. We just have to do the best we can. I have done a lot of research over the past three months. I would be willing to send some links along to you concerning diets and supplements pertaining to triple negative. If you are interested, let me know and I'll private message you. I just did my first chemo today. Went very well. Now just waiting to see what the next days have in store for me. Good luck to you. Didn't you start today, also

KBeee

Oncotype is high because you are ER negative. The oncotype is typically only done for ER+ to determine if chemo would be of benefit, so I am not sure why they ordered it, other than the PR+ throws a little curveball in there. If ER-. chemo is typically a given. I am thinking they would treat you as triple negative, and chemo is usually very effective on it. Best wishes.