Anyone had their teeth/jaw bone affected by Taxotere?

leftduetostupidmods

I had total bridges (both on upper maxillary and lower maxillary) done 15 years ago, that means that all my teeth had root canals, and were "chiseled" and covered with a total bridge with metallic base and porcelain veneers. It was done in Europe, and I understood this is a procedure that is simply not done here. Anyway. That worked very good for me until I had chemo. A couple years after chemo, suddenly my upper bridge fell off while I was eating and I discovered that I had only 4 teeth left on the upper maxillary - the rest were gone, just the roots remained. Of course to treat that, only dental surgery (that only an academic medical center can perform, not your run-of-the-mill dentist office) to remove the roots and put dentures in. Soon after my lower bridge followed and the same had happened.

My oral surgeon said that he had seen that happening, and worse. I know that on the Taxotere side effects, jaw bone necrosis is mentioned as a rare but severe side effect. But couldn't find anything about teeth.

Anyone else had this experience? Maybe not as severe as mine, but did chemo affect your teeth in any way?

Also, I got apical fibrosis in my lungs from Cytoxan. Cyclophosphamides are known as malignant agents for pulmonary fibrosis. I discovered mine after I started having episodes of wheezing when I was laying down. A pulmonary function test and MRI/CT confirmed it.