Eggs AFTER chemo?
I'm 32 and I was diagnosed in November 2014 with a Grade 3 IDC, Ki67 was 72%, ER weakly positive (17%), PR-, HER2- and also discovered I am BRCA1+. They basically treated me as a triple negative but I will still be taking Tamoxifen for 5 years due to the weakly positive ER. My MO said I won't receive as much of a risk reduction as someone who is strongly ER positive, but it is a reduction nonetheless.
I finished chemo at the end of May and had a bilateral mastectomy in June. I was getting monthly Lupron shots from December to May to try and protect my ovaries. I had my AMH checked prior to starting chemo and it was 4.9. My period hasn't returned yet, but I had some bloodwork done by a fertility doctor to get an idea of what things look like as the last Lupron from May should have worn off by now. My FSH is elevated at 11.1 (it should be at 5 or 6 for someone my age) so my fertility doctor isn't expecting my AMH to be good (he expects that it will be less than 1... yikes). He basically implied that we will have a very hard time getting a take home baby with my eggs with the way my bloodwork looks, even without having the AMH values back yet. He said my AMH would need to be 2 or 3 in order for it to be worth trying.
Anyway, I am going to be doing radiation starting in August and will finish in September, at which point I will start Tamoxifen. I thought this would be a good window to try and get some eggs, as I did not have the opportunity to harvest eggs prior to chemo due to the urgency of starting treatment. I thought I had read prior to starting treatment that chemo only reduced the number of eggs you have, not the quality of the remaining eggs. But then I just read something the other day saying that you shouldn't get pregnant within 6 months of having chemo to allow the "damaged eggs" to get out of your system. Is this true? Would trying to get some eggs right now be a terrible idea? Now I'm very conflicted about whether or not I should even try, and if I did get eggs and successful embryos, would they end up with something wrong with them from the chemo?
My MO wants me to start Tamoxifen within 3 months from the date of surgery and I don't think he's going to be thrilled with the idea if I wanted longer than that to get past the 6 month post chemo mark, and honestly with my eggs not looking great anyway, I don't know that it would even work out and be worth the risk of delaying Tamoxifen.
I am planning on going off of Tamoxifen after 2 years to try for a pregnancy (which my MO has given his blessing for) and then go back on after I have a baby. Unfortunately, I just don't know if I'm even going to be fertile 2 years from now even it's already looking a little gloomy now.
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