LVI (lymph vascular invasion)

Nancy2581

just curious how many of you had LVI present in your tumor?  I do and my onc never mentioned it.  How significant is it?  Dr. Google (I know shame on me) says it's not good.  I also read that if you have lymph node involvement you probably have LVI but it wasn't  detected, but I've read of ladies having lymph node involvement and no LVI. Geez my cancer was grade 1 - how is that not considered aggressive if I had LVI and a positive lymph node?

Nancy

spendygirl

I do, but negative nodes.  I've done tons of reading and it scares the heck out of me, but onc is not concerned at all about it.  So I just trust him and try not to freak out about it (easier said than done)

Nancy2581

thanks spendygirl - my onc never even mentioned, but it scares me too

Nancy

Lenn13ka

Hi Nancy - I had extensive LVI and a positive node and grade 2/3 tumor. I agree that reading about this on the internet is scary but my 2 MO's ( from different institutions) were never overly concerned, although it was discussed when considering treatment options. 

inks

LVI here too with only micromets in one lymph node. Most of the info I found about LVI was also about poorer prognosis but I believe there is way more to it. One study noted that LVI may be an indicator of poorer outcome for older women, but when it came to younger women it was not a significant factor since younger women had more agressive tumors to begin with. Go figure. Mine was brought up by the RO when I questioned the need for radiation.

Nancy2581

thanks Lenn13ka and inks-the next time I see my onc I will ask her

Nancy

ThinkingPositive

I had LVI present indicated on my pathology report in addition to one lymph node out of 17 positive.....8mm with encapsulated extension. I am stage 2a, grade 3..so naturally I read online about it and scared the daylights out of me with all I read.. My oncologist said not to get hung up on that after started questioning it...it wasn't until the next meeting with him that I actually was aware and wondered why they weren't more concerned. Even my breast surgeon when she went over the report with me told me that all the cancer was removed with mastectomy and with clear margins.....in fact MO never mentioned it when talking about regimens that I could chose.. NCCN guidelines say ACT or TC is acceptable regimens with ACT being Standard of Care with heart risks.. I opted for the TCx4 and am wondering if that makes a difference with the regimens...after reading everything on line and seeing how many people do ACT for node positive...I am doubting my decision.