Great article about the role of the progesterone receptor

lekker

I came across this and found it to be a fascinating look at the significance of PR. It's extremely technical, so not a light read, but very informative.  It talks about the role of progesterone even in PR negative breast cancers and how it plays into multiple paracrine pathways including RANK/RANKL (which is targeted with xgeva/denosumab).  

http://www.biomedcentral.com/1741-7015/12/32

SpecialK

lekker - reposted your link so it is clickable:

http://www.biomedcentral.com/1741-7015/12/32