What foods are you eating to reduce recurrence?

BrooksideVT

Wow, Kimag, that sounds like fun!  I had no idea it was so easy.  Are there any health issues we need to watch out for?  And what about when it's become sauer--Do you eat it right away, or does it keep fermenting away in the fridge?

In my family, we've always had sauerkraut with turkey.  Just add a little gravy and it's absolute heaven!

agness

I've come across some studies and things that have been linked to metastasis:

• inflammation
• iron deficient anemia
• hypomagnasemia

Inflammation -

• they are finishing up a study looking at fish oil and COX2 inhibitors (ibuprofen, etc.), results should be available in august 2015
• fish oil (omega 3) reduces inflammation; try it in capsule form and store it in the freezer, taken on a full stomach reduces fish burps. Not sure about taking ibuprofen but since I didn't take it before I figure I can be a little more liberal in its use.

Iron deficient anemia -

• in mouse studies anemia (measured by low serum ferritin as RBC might not show it) increased the risk of mets.
• Getting enough zinc, vitamin c, lowering copper intake, b-vitamins and restoring proper gut flora with probiotics can help. Ferritin is packed up in the gut walls.

Hypomagnesemia (Low magnesium)

• - associated with increased mets, plus magnesium is important nutrient for building strong bones and many people are deficient.
• - magnesium is a component in chlorophyll so eat your green veggies, modern farming practices inhibit magnesium absorption by plants so supplementing is important. Epsom salt soaks and magnesium oil are great transdermal ways to increase the amount of magnesium in the body. Coconut oil improves magnesium absorption, take a spoonful each day or so. Natural Calm is a powered magnesium that you mix with water; studies have shown that frequent low dosing of magnesium is better than large doses which instead trigger the body to flush out the excess.

HTH

lyzzysmom

Well I am not much of a cook but I am trying to eat healthier, especially as I decided to take a break from Tamoxifen. Have not slept more than 5 hours in months and I am so tired but wired. Have tried a raft of things from melatonin to prescription and nothing works and enough was enough for a bit. Anyway I exercise regularly but still felt horribly cranky and miserable at the gym today and I am sure a lady I started venting to must have thought I was rather weird. Tamox withdrawal I think BUT before I went home I went to the vitamin shop to replenish my fish oil, calcium and D3 then went to the supermarket and picked up some things for a nice salad tonight.

I got organic beets and microwaved and peeled them, not something I have done before, then I also cooked the greens that were attached as I read that they are good too. I nearly destroyed my container but managed to pop it back into shape with my foot!!! Then I added just a little bacon salt and a teaspoon of light butter (yes I know..) with canola oil and ate the greens. They were delicious and I managed not to paint the kitchen red with the beets which is good. Tonight they will go with my salad.

lyzzysmom

kayb. thank you! I will try that. I realized in reading your post that I did take 5 HTP before dx but I think it was contraindicated during rads of all things so its been a while and I had forgotten all about it so its time to start again and I will add the L-Theanine! Sleep deprivation is turning me into a cranky old lady LOL. I do have an eye shade but need something better as DH likes a bright night light. I actually like it pitch black so we have to compromise!

abigail48

there are lots of foods I think that will give iron: mullberry juice, tomatoes, raspberries, beets all those red fruite & vegetables probably beets the best also probably greens such as swiss chard

kimag

Brookside if you put the saurkraut in the fridge you will slow down fermentation process so it should last longer in not as saur state we would eat all before it gets to saur or use more saur for a soup (there is a soup we make with saurkraut or pickled cucumbers) or you can put it to the jars, pasteurize it and store - pasteurization stops fermenting too.

lyzzysmom - I heard that beets greens are very healthy was not able to get myself in to eating it too often, I also now that blackberry currant juice is very healthy as there is a lot of antioxidants in it, it is hard to find though

yoga_girl

Hypomagnesemia (Low magnesium)

-additional options:

Magnesium Oil (spray) - my massage therapist applies two spray pumps on the bottom of each foot for the segment of reflexology I receive; I apply it every other night, put on my night socks and enjoy the benefits of the magnesium absorbing through the skin.

http://www.ancient-minerals.com/products/magnesium-oil/

http://www.massagetherapy101.com/massage-techniques/reflexology.aspx

http://www.ancient-minerals.com/products/magnesium-oil-reviews/

agness

I had insomnia issues for years before my diagnosis, ever since my first pregnancy. Once I started on magnesium and zinc supplementation I started sleeping again. A study done on nursing home residents showed that zinc and magnesium helped them to sleep better without medication. Magnesium is a precursor to serotonin and melatonin.

Carboplatin depletes magnesium as I bet many other chemo drugs do as well.

flaviarose

Hello kimag, would you be willing to share the sauerkraut soup recipe? I have a couple of jars in my fridge that are getting kind of old.

agness

It is good that you kept working at it kayb. I'm glad you are finally getting decent rest.

Hopeful82014

Four minor - you mentioned ginger/turmeric tea a while back. Can you suggest any brand names? Ginger tea is readily available here but haven't seen turmeric tea. However, I'm sure I could order it.

Thanks a lot!

golilly2

Hello hopeful 8201,

Have you tried Chaga Tea? This tea has been Used for years in Siberia for breast cancer. I looked it up on line and it has amazing ingredients for a cancer fighter. I buy it in powder form and let my tea soak , and then I drink the batch throughout the next two days. Good old green tea is still a nice standby tea too. Keep the daily lemon juice in your water bottle ...

yoga_girl

Turmeric Tea-article
http://www.drweil.com/drw/u/ART02833/turmeric-tea

brands/suppliers:

Swanson-

http://www.swansonvitamins.com/swanson-organic-turmeric-tea-20-bags-s?SourceCode=INTL415&mkwid=tQBndP0G&pcrid=4261374727&utm_source=bing&utm_medium=cpc&utm_term={keyword}&utm_content=415-01+Herbs&utm_campaign=415-01+Product+Ads&CA_6C15C=530002460000015733

Republic of Tea-

http://www.republicoftea.com/product.aspx?p=V20245

Vitamin Shoppe-Rishi Tea

Turmeric / Ginger

Turmeric / Lemon

http://www.vitaminshoppe.com/p/rishi-tea-organic-turmeric-ginger-tea-2-5-oz-loose-leaf-tea/r8-1040?sourceType=sc&source=SHOP&cm_mmc=Shopping-_-NA-_-NA-_-NA&utm_source=Shopping&utm_medium=CSE&utm_campaign=Rishi_Tea&utm_content=R8-1040&mr:referralID=0ce2dd3d-8403-11e4-8d82-001b2166becc#.VI5JAE1gNjo

http://www.amazon.com/dp/B0083PT6S6/ref=asc_df_B0083PT6S63392974?smid=ATVPDKIKX0DER&tag=pg-645-86-20&linkCode=df0&creative=395097&creativeASIN=B0083PT6S6

Hopeful82014

Go Lilly & Yoga Girl - thanks SO much for the suggestions and the links!! Those are both intriguing and helpful. I'll enjoy exploring them. Hadn't heard of Chaga Tea but plan to give it a try. Thanks again, and best to both of you.

Cee67

Kimag, I watched a vid on You Tube tonight about water alkalizers and ionizers. Your comment about antioxidants made me think of it. The woman in the video claims that if you drink alkaline/ionized water you're drinking antioxidants all day long!

I am considering investing in one of the machines. There's a health store where we can buy alkaline water, but I don't want to go over there all the time.

Here's the video link if anyone would like to see it:

https://www.youtube.com/watch?v=SAWEZcgPDLk

Traveltext

I looked into this. Here is what I found.

What Is Ionized Water And Are There Real Health Benefits From Drinking This Type Of Water?

What is "ionized water"? The term is essentially meaningless. True, it is possible for water to contain dissolved ions (electrically-charged atoms or molecules), but that's something else again. Almost all waters found in nature acquire ions such as calcium and bicarbonate as they come into contact with rocks and sediments. Even the purest rainwater contains some hydrogen- and bicarbonate ions that are formed when it picks up carbon dioxide in the atmosphere.

ionsPure water consists almost entirely of H2O molecules loosely bound in a network-like structure in which individual molecules are constantly changing partners. Water molecules exhibit a very slight tendency to dissociate ("ionize") into hydrogen ions and hydroxide ions: H2O ; H+ + OH- but the extent of this reaction is severely limited by the fact that the reverse of this reaction is much more rapid, so that on the average, only about two out of every billion H2O molecules is dissociated.

No electrical device or chemical additive is capable of increasing these ion concentrations in pure water above this very minute level which is so small that for most practical purposes pure water can be considered to be ion-free, as evidenced by the fact that it will not conduct an electric current.

Acidic and alkaline water, pH all water and all aqueous solutions contain both H+ and OH– ions. If the quantity of H+ exceeds that of the OH-, the water is said to be acidic. If there are more OH- ions than H+, the water is alkaline. Pure water, which contains equal numbers of both ions, is said to be neutral. Chemists express the degree of acidity or alkalinity on the pH scale which runs from about 0 to 14. Acidic solutions have pH values of less than 7, alkaline solutions more than 7.

Pure water, being neutral, has a pH of exactly 7. Each unit on the pH scale represents a hundred-fold change in the ratio of the two kinds of ions; for example, if the pH is 8, there are 100 times as many OH- ions than H+ ions (that is, [H+] = 10-8, [OH-] = 10-6.) Whether a water is acidic or alkaline, it will always contain equal numbers of positive and negative electric charges.

Since alkaline water contains an excess of OH- ions, it must also contain some other kind of positive ion in addition to H+ in order to equalize the opposite charges. This extra positive ion is almost always a metal ion such as sodium, calcium or magnesium. Similarly, an acidic water must always contain negative ions in addition to OH-; the most common of these is bicarbonate HCO3-. This means that waters whose pH differs from 7 are never "pure" in the chemical sense.

"Ionized water" is one of many products and panaceas that the wonky-water wellness industry flogs onto the large segment of the general public that lacks the scientific background to distinguish scientific fact from pseudoscientific hype when the two are closely intertwined. What most of these treatment devices actually sell are grossly overpriced electrical devices that purport to produce "ionized" and alkaline water by the process of electrolysis.

Here's basically the bottom line when it comes to ionized water...

"Ionized water" is nothing more than sales fiction; the term is meaningless to chemists.

Most water that is fit for drinking is too unconductive to undergo significant electrolysis.

Pure water can never be alkaline or acidic, nor can it be made so by electrolysis.

Groundwater containing metal ions such as calcium and magnesium can be rendered slightly alkaline by electrolysis, but after it hits the highly acidic gastric fluid in the stomach, its alkalinity is gone.

The idea that one must consume alkaline water to neutralize the effects of acidic foods is ridiculous; we get rid of excess acid by exhaling carbon dioxide.

The claims about the health benefits of drinking alkaline water are not supported by credible scientific evidence.

There is nothing wrong with drinking slightly acidic waters such as rainwater. "Body pH" is a meaningless concept; different parts of the body (and even of individual cells) can have widely different pH values.

If you really want to de-acidify your stomach (at the possible cost of interfering with protein digestion), why spend hundreds of dollars for an electrolysis device when you can take calcium-magnesium pills, Alka-Seltzer or Milk of Magnesia?

Electrolysis devices are generally worthless for treating water for health enhancement, removal of common impurities, disinfection, and scale control.

In the end, it's better to keep your money in your pocket before shelling out a lot of money on an ionizer.

Cee67

Heh, I just got done writing a far less detailed post that said similar. I do know that there is debate on alkaline water - some swear by it - and there is a gal here who has had some amazing results drinking baking soda in water (something else I've read is worthless and dangerous.)

Why does alkaline water cure one person but not another? Chemo is the same - some have terrific results and others don't. Until we start treating cancer on an individual basis (in the pipeline) we're all going to be feeling around in the dark wondering what treatment works best for whom.

Unfortunately the only way we'll discover that is to try different things and yes, that comes with expenditure. Everyone is taking supplements and they're all horribly overpriced IMO. I just bought about 50% of the supplements I should take and that was $200 for a month, or less if I take more than suggested which is always recommended.

She had some probes in the video to measure PH and oxidation. Do you think that was fake?

Fourminor

Hopeful,

I found this in the natural food store. Its three ginger with turmeric

http://www.pukkaherbs.com/pukka-products/pukka-tea...

Hopeful82014

Thanks, Fourminor - that looks good! I'll see if the brand is available locally, and order it if not. I'll let you know how it is. For me, a little turmeric goes a LOOONG ways, so combining it with ginger has a lot more appeal that consuming it solo, or even in capsules.

That company has some other teas that look like fun, too.

Traveltext

Cee67. Lots of things work on some people and not on others and I guess that's why you suggest that we have to start treating cancer on an individual basis. Most of us go through the scientific cure for our different grades of BC, and this more or less works thankfully. Then we start looking around to find things to take that might stop a recurrence. Half of the extra stuff we take is likely wasted, but since we don't know which half is useless, we continue with everything! My one "supplement" is papaya leaf tea which is used in Asia as a cancer treatment and which a Japanese study shows has some efficacy. Now, I'll never know if it is working. And if my cancer returns, is it useless or has it kept something else at bay.

We really all have to chose a path and try our best to get on with things IMO. Actually, I posted the alkaline water article since I researched it recently and found the promotional science was dodgy. But now I really don't think it's right to put someone off a course of action if they are keen to try something, since there are amazing stories of people seemingly being cured by various things.

pipers_dream

cee and traveltext, I recently read Radical Remission and she said that one of the nine things that people who heal spontaneously do is to walk this walk with their intuitive mind open. I do this a lot-- I read widely in this but in a kind of scattered fashion and when an idea grabs hold of me I follow thru. Sometimes it's physical, like a supplement I need to take. Sometimes it's emotional like getting control over stress and sometimes it's making sure I fill a need or try to which is why I'm continuing to try to date even with this awful thing happening to me. That's why it seems so pointless to tell someone that what they're doing is wrong. We can't know that. So yes, I think you two are on to something. And yeah TT, even if we do manage to heal ourselves holistically we'll never know for sure what did it and that's why science doesn't trust it.

Cee67

Awww Traveltext, I am not fussed at all by what you posted and I read everything! We need to do that anyway but *especially* with Altmed. All we can do is try! My mother, bless her, wants to buy me the ionizer and I advised her to hold off because I need to investigate further. Maybe I will get one and maybe I wont I've told her if she wants to buy me something I'm considering a portable sauna (I don't have room in my apt for the nice cabinet kind). It looks a little cheesy sitting with a tent around you, but people have been using saunas for centuries and with my use of cannabis oil I could lighten the burden on my liver with some good sweating.

-----Actually, I posted the alkaline water article since I researched it recently and found the promotional science was dodgy. But now I really don't think it's right to put someone off a course of action if they are keen to try something, since there are amazing stories of people seemingly being cured by various things.----

We are all helping each other. There is no way I'd be able to find articles about things all by myself. With everyone here posting things they find it really helps! Knowledge is power and I may discover water ionization is a crock and move on to something I feel is better (like the sauna ) But I appreated very much what you posted. Just because I debate in return doesn't mean I didn't appreciate your effort, and I thank you for the article and the science behind it

yoga_girl

Mushroom Supplements

Anyone have suggestions on benefits and which ones.  Does blood type factor in on which one works better than another or the combination of several. 

Would like to know more about what is being used by BC patients. 

flaviarose

I don't know anything about blood type and which mushrooms are better. I've heard that many are very good. And there is an extract called AHCC which is what my doctor said was "evidence based." I've heard that chaga is good for breast cancer. Also turkey tail, maitake, and reishi. I've bought different products. My most recent purchase was this one, it claims to have been tested for heavy metals, etc. I guess you never know with supplements.....: http://store.naturalnews.com/Organic-Seven-Treasur...

I have also used this product, as well as individual mushrooms from this company:

http://www.amazon.com/Fungi-Perfecti-Community-Veg...=sr_1_4?ie=UTF8&qid=1418848735&sr=8-4&keywords=mushroom+complex

Cee67

Does anyone take milk thistle? I bought some because I am worried about my liver. I have read that our livers and colons are cleansing organs and that support for them is not necessary, but then I read other things that say it is beneficial.

I read (I think it was on the Susan Komen site) that milk thistle can increase estrogen levels somewhat and should not be used by women with estrogen driven cancers. Yet I've read many more articles that say it is beneficial if you have cancer, granted the things I was reading in favor of it did not mention specific types of cancer - just cancer in general.

Thoughts?

formydaughter

yoga girl - Turkey Tail mushrooms are supposed to be anti-BC. The trusted source for them is Host Defense. (I've heard that you have to be careful of impurities if you purchase from overseas, but the Host Defense product is grown in the US.) This product was part of a NIH funded study for BC patients having radiation or chemo. Look for Paul Stamets. Here is a link to his TED talk:

http://www.bastyr.edu/news/general-news-home-page/...

Host defense link:

http://hostdefense.com/products/mushroom-capsules/item/turkey-tail?category_id=4

flaviarose

Milk thistle is another one of those controversial items. When I first was diagnosed I sought the advice of a nutritionist and she put me on milk thistle, giving me the following information. When I was going through chemo I was taking it because I wanted to protect my liver. Afterwards I stopped after hearing that it promoted estrogen. There is so much bad information out there, you don't know what to believe.

RE Silymarin and cancer (plus good for your gallbladder/liver): 1. Anticancer Res. 2011 Nov;31(11):3767-73.

Silibinin suppresses EGFR ligand-induced CD44 expression through inhibition of EGFR activity in breast cancer cells.

Kim S, Han J, Kim JS, Kim JH, Choe JH, Yang JH, Nam SJ, Lee JE.

Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-Gu, Seoul, 135-710, Korea.

CD44, the transmembrane receptor for hyaluronan, is implicated in tumor cell invasion and metastasis. The expression of CD44 and its variants is associated with poor prognosis in breast cancer. Here, we investigated the effect of silibinin (a polyphenolic flavonolignan of the herbal plant of Silybum marianum, milk thistle) on the epidermal growth factor (EGF) ligand-induced CD44 expression in human breast cancer cells. The levels of CD44 mRNA and protein expression were greatly increased by EGF and by TGF-a in SKBR3 and BT474 breast cancer cells. In contrast, EGFR ligand-induced CD44 expression was reduced by EGFR inhibitors, AG1478 and lapatinib, respectively. Interestingly, we observed that EGFR ligand-induced CD44 and matrix metalloproteinase-9 (MMP-9) expression was reduced by silibinin treatment in a dose-dependent manner. In addition, silibinin suppressed the EGF-

induced phosphorylation of EGFR and extracellular signal-regulated kinase1/2 (ERK1/2), a downstream signaling molecule of EGFR. Therefore, we suggest that silibinin prevents the EGFR signaling pathway and may be used as an effective drug for the inhibition of metastasis of human breast cancer.

PMID: 22110198 [PubMed - indexed for MEDLINE]

2. Anticancer Agents Med Chem. 2010 Mar;10(3):186-95.

Silibinin--a promising new treatment for cancer.

Cheung CW, Gibbons N, Johnson DW, Nicol DL.

Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia. catherine_cheung@health.qld.gov.au

Silymarin and its major constituent, Silibinin, are extracts from the medicinal plant Silybum marianum (milk thistle) and have traditionally been used for the treatment of liver diseases. Recently, these orally active, flavonoid agents have also been shown to exert significant anti-neoplastic effects in a variety of in vitro and in vivo cancer models, including skin, breast, lung, colon, bladder, prostate and kidney carcinomas. The aim of the present review is to examine the pharmacokinetics, mechanisms, effectiveness and adverse effects of silibinin's anti-cancer actions reported to date in pre-clinical and clinical trials. The review will also discuss the results of current research efforts seeking to determine the extent to which the effectiveness of silibinin as an adjunct cancer treatment is influenced by such factors as histologic subtype, hormonal status, stromal interactions and drug metabolising gene polymorphisms. The results of these studies may help to more precisely target and dose silibinin therapy to optimise clinical outcomes for oncology patients.

PMID: 20015009 [PubMed - indexed for MEDLINE]

3. Mol Cancer Ther. 2009 Jun;8(6):1606-12. doi: 10.1158/1535-7163.MCT-08-1152. Epub 2009 Jun 9.

Silibinin inhibits translation initiation: implications for anticancer therapy.
Lin CJ, Sukarieh R, Pelletier J.
McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada.

Silibinin is a nontoxic flavonoid reported to have anticancer properties. In this study, we show that silibinin exhibits antiproliferative activity on MCF-7 breast cancer cells. Exposure to silibinin leads to a concentration-dependent decrease in global protein synthesis associated with reduced levels of eukaryotic initiation factor 4F complex. Moreover, polysome profile analysis of silibinin-treated cells shows a decrease in polysome content and translation of cyclin D1 mRNA. Silibinin exerts its effects on translation initiation by inhibiting the mammalian target of rapamycin signaling pathway by acting upstream of TSC2. Our results show that silibinin blocks mammalian target of rapamycin signaling with a concomitant reduction in translation initiation, thus providing a possible molecular mechanism of how silibinin can inhibit growth of transformed cells.

PMID: 19509268 [PubMed - indexed for MEDLINE]

4. Cancer Invest. 2011 Jan;29(1):12-20. doi: 10.3109/07357907.2010.535053.

Silibinin-induced apoptosis in MCF7 and T47D human breast carcinoma cells involves caspase-8 activation and mitochondrial pathway.

Tiwari P, Kumar A, Balakrishnan S, Kushwaha HS, Mishra KP.

Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India.

Silibinin, a natural flavonoid, under phase I/II clinical trial in prostate cancer patients was aimed to evaluate its chemotherapeutic potential in human breast cancer cell MCF7 and T47D. Results showed that T47D cells were found to be more sensitive to silibinin than MCF7 as observed by proliferation, clonogenic, and apoptotic assays, which was abrogated by pan-caspase inhibitor but remained unaffected by p53 inhibitor. Apoptotic events in both cell types differ temporally and also by magnitude that involved mitochondrial and caspase-8 activation pathway. These results have relevance in understanding silibinin treatment to breast tumor.

PMID: 21166494 [PubMed - indexed for MEDLINE]

5. Cell Signal. 2012 Dec;24(12):2291-6. doi: 10.1016/j.cellsig.2012.07.009. Epub 2012 Jul 20.

Silibinin inhibits Wnt/ß-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells.

Lu W, Lin C, King TD, Chen H, Reynolds RC, Li Y.

Department of Biochemistry and Molecular Biology, Drug Discovery Division, Southern Research Institute, Birmingham, AL 35205, USA.

Silibinin is a natural compound isolated from milk thistle seed extracts, and has traditionally been used as a hepatoprotectant. A number of studies have also established the cancer therapeutic and chemopreventive role of silibinin in both in vitro and in vivo models. The low density lipoprotein receptor-related protein-6 (LRP6) is an essential Wnt co-receptor for the Wnt/ß-catenin pathway and represents a promising target for cancer prevention and therapy. In the present study, we found that silibinin was able to repress endogenous LRP6 expression and block Wnt3A-induced LRP6 phosphorylation and Wnt/ß- catenin signaling activation in HEK293 cells. Importantly, silibinin was also able to suppress endogenous LRP6 expression and phosphorylation and block Wnt/ß-catenin signaling in prostate cancer PC-3 and DU-145 cells and breast cancer MDA-MB-231 and T-47D cells. Mechanistically, silibinin inhibited LRP6 promoter activity and decreased LRP6 mRNA levels in prostate and breast cancer cells. Finally, we demonstrated that silibinin displayed anticancer activity with IC(50) values comparable to those shown to suppress LRP6 expression and Wnt/ß-catenin signaling activities in prostate and breast cancer cells. Our data indicate that silibinin is a novel small molecule Wnt/ß-catenin signaling inhibitor by suppressing Wnt co-receptor LRP6 expression at the transcription level, and that the anti- cancer activity of silibinin is associated with its inhibitory effect on Wnt/LRP6 signaling.

Copyright © 2012 Elsevier Inc. All rights reserved.

Cee67

Thank you for this article, but I don't really understand it. It *looks* like it says that milk thistle has anticancer properties. It's very confusing because just when I think I've found something that would be beneficial, I see other articles saying to avoid it.

It's like the X-Files - "The truth is out there."

Now we just need Mulder and Scully to go out there, find it and come back here and tell us all what to do!

flaviarose

I know, Cee67, it is very difficult to know what is actually true. There are many half truths out there, and not enough research on herbs.

Nash54

yoga girl....I was wondering which mag spray you use. The original or the ultra? I've been using mag supplements and have had great success with leg cramps, heart palpitations and regularity. Thought I might try the spray instead.