New Drug Target ... Test for Hormone Therapy Resistance

cp418

http://www.sciencedaily.com/releases/2013/04/130401151035.htm

New Drug Target Companion Prognostic Test for Hormone Therapy Resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.

cp418

http://www.sciencedaily.com/releases/2012/08/120830105427.htm

Possible Therapy for Tamoxifen Resistant Breast Cancer Identified

A study by researchers at the Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC -- James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate. It also suggests that an experimental agent might offer a novel targeted therapy for tamoxifen-resistant breast cancer.