Complete Tumor Sequencing: $4000-$5000

jenrio

http://www.reuters.com/article/2012/07/12/us-completegenomics-shares-idUSBRE86B0PQ20120712

jenrio

http://www.forbes.com/sites/matthewherper/2012/07/13/can-complete-genomics-escape-the-valley-of-death/

Good quality data, but having trouble convincing doctors.   Here is where patients could come in.   Patients have the right and the duty to demand the newest and best and cheapest technologies, to encourage innovation and save money for themselves and for the system.   Illumina's 90% market share is not healthy for the development of this nascent market and notice how Illumina had to drop their price from $20000 to $4000 due to the new entrants into this market.    Quote from wikipedia:

In June 2009, Illumina announced the launch of their own Personal Full Genome Sequencing Service at a depth of 30X for $48,000 per genome,[1] and a year later dropped the price to $19,500.[2] This is still too expensive for true commercialization but the price will most likely decrease substantially over the next few years as they realize economies of scale and given the competition with other companies such as Complete Genomics and Knome.[3][4] As of May 2011, Illumina reduced the price to $4,000.[5][6] 

jenrio

Bump.   This is the one news from this week that I think more people should be aware of.    Why is nobody helping to bump this thread?

So far, clinical trials rarely used whole genome sequencing in anyway. Why? It costs 20k even 1 year ago. Even researchers have to share the whole genome sequencing service and wait long time for their slots. Kind of like what mainframe computers was 40 years ago, IBM predicted there should be no more than 1000 computers for the global market. Instead with the maturation of technology, many people have multiple computers in their homes.

Affordable whole genome sequencing will change how we understand and treat cancer: drug selection, understanding drug resistance. The price 4000 is right, and dropping fast with more competitors.   When it costs $100, we could afford to sequence not just one part of our tumor, we could sequence multiple parts of our tumor and have clinical trials that requires whole genome sequencing to understand why or why not a given drug works for certain people.

All new born babies are ugly. Genome sequencing is not answer to all our questions, but the data will be extremely useful. Remember the Metabric study? It was a major reclassification of BC based on full genome sequencing. They are now moving to check RNA too.

$1000 even $100 full genome sequencing is the future and will change the face of health care. Care for a wager?

ihatesnowihatesnow

http://www.nytimes.com/2012/07/08/health/in-gene-sequencing-treatment-for-leukemia-glimpses-of-the-future.html?_r=1&smid=pl-share

ihatesnowihatesnow

and genome sequencing  will become cheaper as computers become cheaper and more powerful ...........research like this needs huge computing power        like this one      http://boinc.bakerlab.org/rosetta/

ihatesnowihatesnow

 http://video.search.yahoo.com/video/play;_ylt=A2KLqIDzoQRQlhwA2uD7w8QF;_ylu=X3oDMTBvbHJtNTJvBHNlYwNzcgRzbGsDdmlkBHZ0aWQDVjEyOA--?p=rna+cancer&vid=28BBE3437DBCBC1EFA8F28BBE3437DBCBC1EFA8F&l=&turl=http%3A%2F%2Fts3.mm.bing.net%2Fvideos%2Fthumbnail.aspx%3Fq%3D4561423416951074%26id%3Df20f139f692891282668c016424e7003%26bid%3Dj%252foevLx9Q%252bO7KA%26bn%3DLargeThumb%26url%3Dhttp%253a%252f%252fwww.youtube.com%252fwatch%253fv%253dr-BRcktorKE&rurl=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3Dr-BRcktorKE&tit=DNA+4%2F5+Curing+Cancer+%28PBS+Documentary%29&c=28&sigr=11akiaorq&

http://video.search.yahoo.com/video/play;_ylt=A2KLqIALoQRQgQ8AHjP7w8QF;_ylu=X3oDMTBvbHJtNTJvBHNlYwNzcgRzbGsDdmlkBHZ0aWQDVjEyOA--?p=rna+breast++cancer+protein&vid=A6D229B685CF2FE07F6AA6D229B685CF2FE07F6A&l=&turl=http%3A%2F%2Fts2.mm.bing.net%2Fvideos%2Fthumbnail.aspx%3Fq%3D4528425178103949%26id%3Db80b23f4b28b30b299c4f85117c4f47f%26bid%3Dan%252fgL8%252bFtinSpg%26bn%3DLargeThumb%26url%3Dhttp%253a%252f%252fwww.youtube.com%252fwatch%253fv%253dtG5c4_OiJNs&rurl=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DtG5c4_OiJNs&tit=The+New+Biology+of+Breast+Cancer+--+Sloan-Kettering&c=1&sigr=11au82j9e&