One more question...

itsjustme10

I apologize for being a pest, but you ladies are so knowledgeable about this stuff, so here goes...

DIM vs. I3C  which would you choose?

I spoke with the integrative medicine department (they make you talk to a nutritionist who won't give too much information, so as not to step on the MO's toes), and got these 2 supplement names out of him.  I read the information on them, but its not going into my little head right now, so...sell me on one or the other, if you can without too much trouble, please...

Yes, I will make my own decision, but I was wondering what the benefits or drawbacks of each are, so if you can tell me of any personal experiences with each, it'll help...

I am glad I spoke with the gentleman today, though, because he told me that these have each had some human trials, where the calcium D-glucarate hadn't, so that was helpful to know.

Thank you.

Anonymous

No need to apologize Itsjustme and no you're no pest Lol

Basically, DIM and I3C are the same, both extracts from cruciferous veges but different molecules

"Significant amounts of diindolylmethane (DIM) are found in cruciferous plants following crushing (8). This contrasts with I3C which, due to its unstable nature, is only transiently present, primarily during digestion (9). I3C is the natural precursor to diindolylmethane, which is formed from a "condensation reaction" in which one I3C molecule combines with another. The resulting diindolylmethane is a "di-indole," or double molecule, formed from two I3C molecules. Release of active diindolylmethane is facilitated by enzymes in the plant and is also due to the action of gastric acid on I3C released during digestion."

So basically, I3C is transformed into DIM by the body, tiz all 

The drawbacks of I3C are as follows:

"I3C requires careful storage, avoiding heat, moisture and light to slow its rapid breakdown on the shelf. Taken as a dietary supplement, I3C requires gastric acid for conversion to active products. I3C is more irritating to the stomach than diindolylmethane, due to its chemical reactivity (11). I3C is also much more prone to interaction with components of food (especially vitamin C), which limits its conversion into diindolylmethane and other condensation products.

Conversion from I3C into diindolylmethane not only requires a precise acidity, it requires time. This conversion may proceed slowly, requiring more time than most foods typically spend in the intestinal tract"

Much more at: http://www.dimfaq.com/site/cruchoice.htm 

I'm taking a DIM combo which includes other goodies.  I believe I read that it may be more expansive than I3C, no sure 

Hope this helps 

itsjustme10

It does help, Maud.  Thank you so much...you explained it really well...its sounds like the smarter move for me would be DIM, so I now have a direction to look in.  Thank you!!  

Anonymous

You're welcome dear, just make sure your DIM does not contain soy, a lot of formulations do, unless you are one who believes in soy for ER pos.  I DO NO believe in soy for ER +