One-two punch knocks out aggressive breast cancer cells

luv_gardening

One-two punch knocks out aggressive breast cancer cells
New MIT study shows that staggered delivery of cancer drugs is far more effective than administering them at the same time.

"The researchers found that giving erlotinib between four and 48 hours before doxorubicin dramatically increased cancer-cell death. Staggered doses killed up to 50 percent of triple-negative cells, while simultaneous administration killed about 20 percent. About 2,000 genes were affected by pretreatment with erlotinib, the researchers found, resulting in the shutdown of pathways involved in uncontrolled growth.

Instead of looking like this classic triple-negative type of tumor, which is very aggressive and fast-growing and metastatic, they lose their tumorigenic quality and become a different type of tumor that is actually quite unaggressive, and very easy to kill."

ETA, the above should be in Italics but it didn't work.