Pathology after surgery

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dventi
dventi Member Posts: 171
edited June 2014 in HER2+ (Positive) Breast Cancer

Scheduled for lumpectomy/ axillary node dissection.  First path report from core biopsy came back Her2+

Does it make sense to confirm that when the path from the surgery is sent out that all 4 tests for HER2 are performed (IHC, FISH, SPot and Inform HER2 Dual ISH).  Does the BS have to request this or should I make sure this is done?

Thanks so much for your input!!!

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  • cindy2
    cindy2 Member Posts: 32
    edited April 2012

    It is standard to run IHC and if the results are equivocal to confirm with FISH.  Running all the tests will not change anything.  Besides with a Her2+ core biopsy, you are likely to get herceptin regardless of the results after surgery.  Tumors can vary and they only test a small portion--therefore it is not very unusual to have a bipsy positive and a tumor negative or vice versa.  I had this situation. My onc said that if there is any evidence of Her2+ they treat with herceptin.  I hope this helps!

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  • dventi
    dventi Member Posts: 171
    edited April 2012

    thanks cindy2 helps out alot.

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