Clinical trials of Her2 drugs on low/non Her2+ BC

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With all the exciting development of TDM-1, pertuzumab for Her2 positive BC, I'm curious to see whether there are clinical trials of Her2 targetted drug for low Her2 positive BC or non Her2 positive BC with Her2+ CTC ?

Mentioned by the CTC news article posted by cp418: 

http://clinicaltrials.gov/ct2/results?term=ctc+tykerb 

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