Why would Myraid need copies on Mom's BRCA+ test?

Candcsmom

Unfortunately, BC has become a reality in my family as we feared it would for years! Maternal great-grandmother and grandmother both died from BC, and mother was diagnosed in Dec. Of course, when tested for BRCA1/BRCA2, she tested positive for BRCA2. Subsequently, one of her sisters has also tested positive. Others are waiting on results. I was tested last Wednesday 2/29 and got a call from my OB doctor (not mom's oncologist) wanting a copy of mom's of test results so that they could know her specific mutation. Myraid was wanting this information. Has anyone had this experience? Only thing I can deduce is I have tested positive and they want to link her test results with mine, since they know her specific mutation is cancer-linked. I'm just ready to find out!!

Mutd

In most cases the Genetic Counselors and the insurance recommend testing for just the one specific mutation which has already been found in your family. It is faster, cheaper, and more sensitive too ( because BRCA2 gene is huge and it takes time and money to look for mutations everywhere in it ... and if the lab knows where to look, they'd check this location twice for added reliability of the result).

 Maybe your ob requested, or your insurance covered, the "one specific mutation site test", but the information about the mother's and aunt's mutation was missing or illegible? Then the lab may need a copy of one of their test results, to make absolutely sure, which of the thousands of known mutations they need to be looking for.

 So it's possible that they still didn't get started on your own test, if there is still some info missing?

Miller1353

I sent a copy of my report to my cousin's oncologist in another state. If she were positive, they need only look to my mutation to see if she inherited it. It saves about $3400 if they look for a single mutation rather than complete an entire genetic panel.

Karmil710

candscmom:  I had a similar thing happen to me:

About 1/2 the people on my father's side of the family have tested (+) for the same BRCA2 mutation.  He has a large family, there are probably more than a dozen BRCA2(+) members.  I only found this out AFTER I was DXed w/BC this fall!

My sister and I were tested around the same time.  My test was done at  my BS's office, my sister's test was done at her PCP's office.  Her test came back (+) and I was still waiting  about a month after the test was done.  My BS office called Myriad, and Myriad said they needed the specific mutation that my sister tested (+) for.  We sent that and I received my BRCA(+) withen days.

I hope you get good news from your test.

learnin

Agree with all of the above. Makes the test more accurate to know which mutation exactly to look for.



I had at least one relative tested negative in the past. Once my mutation was identified, she was retested for that specific mutation, and found to be positive.

hrf

The same thing happened to me. When my test was sent in they needed the results from my first cousin so they could look more precisely. It made it much faster.