Metformin-Anyone on this trial?

Heidihill

I was not prediabetic but my doctor wanted me to take metformin. I lasted about a month on a low dose. Good for you being on the drug 5 years, Chemicalworld! You probably killed a lot of cancer stem cells. These days he just wants me to take metformin when I've been indulging too much like during Christmastime. I do that sometimes.

Anonymous

I started in the trial but then they kicked me out as the said one side of my tumor was too small. Mentioned it to my pcp and he thought it sounded interested and said he’d be happy to prescribe it. So I have been taking it for about 7 years. My Onc said there are good things for er people but details aren’t all in.

The majority of my moms side of the family are all type 2 diabetics, so I figure I’m just being prememptive in a worse case scenario

ChemicalWorld

Jumping back into this thread as not sure where else to post.

Saw another (new) oncologist a couple of days ago to follow up on ten yrs out issues, and brought up the metformin again as i'm still on it (1000mg extended release). The MO told me that the studies ended up showing no benefit and most have been taken off it. She did say however that I should have the discussion about how to go off it with my family doctor which I plan to do (not sure if you're supposed to go off this cold turkey).

Maryjv

Chemicalworld, I have been on Metformin 1000mg BID since diagnosis in 2019-my oncologist refuses to order, I go through my PCP who is hesitant to order but a nephrologist I used to work with recommended I take it for at least 5 years! Please keep me posted on what your PCP plans to do!

ChemicalWorld

maryjv I am being weaned off. I have been on this several years now (well over 5) and while I was previously hesitant, I am feeling ready now and that was the starting point of discussion with my doctor after speaking with my MO. So what my PCP did after I had the discussion, was to reduce the dose to 500mgs ER, will take that for a month and see how it goes, then off.