monitoring supplements/meds interactions

roseroscoe

Hello. I am taking Arimidex (dx May 2007, IDC, 1 cm., grade 3, negative lymph nodes; had lumpectomy, sentinel node biopsy, chemo, radiation; I was 54 and perimenopausal at time of dx and chemo put me in menopause.) I also now consult a holistic MD (referred by my oncologist) for nutritional advice. I am thinking of adding a supplement with the arimidex  (broccoli seed extract - a natural aromatase inhibitor) and monitoring estradiol/estrone with blood tests after starting the supplement. If there were a negative interaction between the arimidex and the broccoli seed extract, how accurate would the blood test estrogen results be? I'm not looking to replace arimidex with the supplement, just use it to enhance the AI effect of arimidex (the supplement works in the liver, not in the adrenals like arimidex).  In addition to the feedback from my oncologist, I would like more opinions as well.  If my estradion/estrone blood tests remain low, can I trust that the estrogen results are accurate -- or could there still be an interaction between arimidex and the supplement that the blood test wouldn't show?  If so, how much chance is there of that?