2 tumors in 1 breast. Need 2 oncotypes?

sgreenarch

I went for a second opinion yesterday and the onc pointed out something that onc #1 missed. I had two tumors in one breast, one 2cm and one 1cm. The oncotype and the markers were done on the larger tumor. Onc #2 wants to see path on the smaller tumor saying SOMETIMES it can be different than the path on the larger tumor and if so, I should consider getting a second oncotype. I know this is kind of highly technical. Just want to know if anyone has had a similar experience. I had thought the path was final, now I'm sending slides out for a second opinion, too. Not sure what the standard of care is in the case of two small tumors, not far from each other in one breast. Thanks.

lana12

I had 3 tumors on my left side 1.5, 1.0, and .4.  On my right side was a tumor .5.  We oncotyped the 2 bigs ones on the left and the small one on the right.  They were all consistant with eachother, 9, 10 and 10.  We did not oncotype the small tumor on the left because the surgeon thought wasn't necessary.  Hope this helps.

lisa-e

I had two invasive tumors.  They were in different quadrents of the same breast and had different er/pr/her stats.  One (1.2 cm) was 98% estrogen postive,  the other (0.8 cm) was 48% estrogen postivive.  Although the standard of care with multricentric cancer is to base treatment on the largest tumor, that didn't make sense to me.  I had oncotype tests done on both tumors.  The score for the larger tumor was 8, for the smaller one 16.  

Before I got the oncotype test for the larger tumor, my onc recomended chemo.  He didn't after he saw the score.  But what I did, to make sure I was comfortable with the no chemo decision, was to run calculations on the possiblity of having a recurrence from either tumor, based on the ocotype scores.  To me that made sense as the two tumors had different biologies.  The results I got from that indicated to me that chemo still wasn't worth the risk.  I would have gotten a 2% to 5% advantage, depending on the assumptions I made.  So the risk was about equal to the chance of permanent side effects from chemo.  

I think it is good your onc wants to considering both tumors.  That makes sense to me.

ToriGirl

My surgery was August 12th and I was just wondering the same thing.  I had 2 masses (one 1.1cm, and the other 6mm) , only the larger one was sent for the Oncotype test.

Just made a call to my oncologist to see why it wasn't done on the 2nd and if they can do it now.  It may play a part in my treatment options, so I just want to know.

Good luck and let us know and I will do the same!

Hugs and prayers,

Tori

sharalou

Had second mastectomy, last Friday. First on 1-2005. IlC, 2 masses approx. 2cm with scattered areas throughout the breast. Had chemo, rads. Low and behold, had MRI 3 1/2 weeks ago, and 2 5mm areas showed up on the right side. Had biopsy, POSITIVE for ILC.  Had sentinel node biopsy-all negative, and remainder of breast tissue-negative.  Going to see surgeon and oncol. on Wed. Hoping and praying NO CHEMO!  Been there and done that.  Does it go alot on t he Onco type(which I don't know that yet). Thanks so much!

sharalou

Didn't have the oncotype because this cancer was estrogen negative.  They only ran one slide out of 2.  Running the other one now, to make sure it's also estrogen negative. My oncl explained (depending on results of second slide), the % is so low with the chemo. I really don't know if it's worth it.  Going back on Wednesday.