What Kind of Chemo for Triple Negative

shafree3

Hi Danielle, my story and chemo plan is very much like yours. Can you tell me how you tolerated it all and how you are now? I had my BLM 4 weeks ago today and my chemo begins the week after thanksgiving. Thx

sparrowabby

Hi,  I know this is long past your post, but I don't get on as much any more.  I am 9 yrs. out from diagnosis.  I was 49.  Back then, all they would say is this is very aggressive and everything (pr/er/ etc. is negative.  I had a lumptectomy, 4 rounds of AC, then 4 more of taxol(hard!) and then radiation.  It was a year of work.  But so far so good, knock on wood.  My main issue right after was pretty severe bone loss, so I always remind people to ask for a bone density after chemo.  Best of luck and positive thoughts to you!

Norma57

I continue to read the boards but think I am the only one on CMF for TNBC.  I just hope I am getting the right treatment for this. This has me concerned!

1angus16

I have just registered with Breastcancer.org and have been looking through everyone's comments.  Was pleased to find someone else with Triple Negative.  In answer to your question, I was put on Cyclophosphamide, Methotrexate, Fluorouracil for six months (two weeks on two weeks off) and this was followed by five and a half weeks radiation treatment.  I opted for a lumpectomy - my surgeon felt it wasn't necessary to have both breasts off at this stage as she said if the cancer comes back, it could reappear in the flaps.  Although this is an older type chemo mix, I have read on an American site that it is very effective - well I certainly hope so. It's a hard battle to fight when there is no other treatment for us.  I hope you are okay.

1angus16

Hi Norma, I have had exactly the same course of chemo as you and according to what I've read of late, it is definitely the right regime to be on.  I am thankful every day that I have such a wonderful oncologist here in Australia. 

1angus16

Hi again Norma.  Just read your last post.  How are you going with your treatment.  I didn't lose my hair when I was on CMF - it thinned out quite a bit though.  Had a bad time with side effects, but doesn't everyone with chemo.  Keep strong.

Norma57

Thanks 1angus 16. I am taking the CMF dose dense, every 2 weeks because this is a recurrence for me. I had breast cancer 15 years ago, never had chemo then, only radiation and 5 years of Tamoxifin.  My recurrence was TNBC. My Surgeon recommended bilateral mastectomy with reconstruction.

My hair is thinning , so I am grateful that I am not going to loose it. Had a rough week last week between  the chemo and the Neulasta shot and the saline fill,  I couldn't eat for 4 days. am going to ask my Onc. for stronger anti-nausea drugs..  Also have the mouth sores and fatigue.

But we are going to beat this thing. You keep storong too.

chapelhill

was your cancer 15 years ago also triple neg?  I have just been dianosed with a new primary 10 years later.  I had triple negative before and was treated with a lumpectomy, AC chemo and radiation.  This time I had 7.2 cm of DCIS with .9 cm of IDC all triple neg.  I have had a bilateral mastectomy and will start TC chemo soon.  My onc is recommending TC - four rounds three weeks apart.  I have asked my Onc to consult with collegues at Sloan and MD Anderson, for their opinions on my treatment and to see if there are any clinical trials I am eligible for.

I didn't realize you can only get Adriamyacin (sp?) once in your lifetime....I am worried since the AC worked before....at least I had no spread and it was gone for 10 years!  

Fighter_34

I'll chime in with my story.

After reading everyone elses posts I got scared and opted for the BMX because I just didn't want to deal w/ BC again down the line. I was told  4 rounds of TC and I wanted SIXXXX. And believe it or not I love my new breast (not done with reconstruction yet), however they look soooo much better than my old triple DDD sometimes F breasts.

When given a DX of cancer you have to face harsh reality and make decisions based on those. Chemo and drugs are hard on the body. I would only want to do this once...

Sending well wishes to us all....