hereditary breast cancer

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manta
manta Member Posts: 3
edited June 2014 in High Risk for Breast Cancer
hereditary breast cancer
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  • manta
    manta Member Posts: 3
    edited May 2010

    hello

    i'm new here... can anyone tell me, for women getting breast cancer before the age of 50, how many get it because of BRCA related mutations? please state your source...

    thanks

    manty 

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  • mlrbelle
    mlrbelle Member Posts: 108
    edited May 2010

    I can't recall the source, but I seem to recall the number being about 5% of BC is related to the BRCA mutations.  There is a really good site facing our risk, I think, that has a lot of information on this.

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  • manta
    manta Member Posts: 3
    edited May 2010

    thanks mlrbelle.

    are you being treated with herceptin? how's the reaction? anyway, best of luck!

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  • MRDRN
    MRDRN Member Posts: 537
    edited May 2010

    Manta,

    Welcome to the site and good question.  I also remember reading that only 5% of all BC is gene related.  The FORCE site is very helpful.  There are also genetic counseling that you can go to to find out your specific risk and a web site to find one in your area.  Hope this helps.  Feel free to PM folks here as I have found everyone to be so helpful to share their own journey.

    Also, search this site as there are many research articles with great side bar interpretations for easier understanding.

    MRDRN

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  • mlrbelle
    mlrbelle Member Posts: 108
    edited May 2010

    Actually, since my nodes were clear and I had bilateral mastectomy (so no real breast tissue left), I wasn't put on herceptin.  My onco felt the risks outweighed the benefits - I would have had to take it had I done a unilateral though as I did have a microinvasion.

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  • MRDRN
    MRDRN Member Posts: 537
    edited May 2010

    That is good to know.  I don't know until after surgery if I will need it.  I am confused by a 6cm tumor was a Stage 0??

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  • Soccermom4force
    Soccermom4force Member Posts: 631
    edited May 2010

    It is thought that 10% of all BC is hereditary...I assume this include other syndromes such as Li-Fraumeni, Cowdens etc..

    Warmly,MarciaCool

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  • kreativek
    kreativek Member Posts: 58
    edited June 2010

    In my genetic counseling session, I think she said that 5-10% of breast cancer can be attributed to the BRCA gene defects.  However, she showed me a pie charge.  One quarter or 25% of breast cancers occur in someone with a family history.  She called these "familiar cancers."  She said they tend to occur later with no increased risk of ovarian cancer.  This explained my family.  We have post-menopause breast cancer and no ovarian cancer.  I tested negative for the BRCA gene.  Many people feel that there may other genetic defects not yet discovered and that can not be tested for yet.

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