Calling all TNs

txjunebug

Special prayers and hugs for LuvRVing, NavyMom and TNBCRuth.  While I haven't been on this thread for long, I am overwhelmed by the caring support from all of you ladies.  I am so very thankful for this support group!

Tookybum  - congrats!!  Just starting my chemo journey.  Get port on Wednesday.

Hoping to get some rest tonight.  Lord help the man from the hospital today who preregistered me for my MRI on Friday!  They got my insurance wrong again for the 4th time and I let him have it.  I probably should call and apologize to him. 

LRM216

Luv:

Please know that my prayers and thoughts are with you for a total resolution to this latest horror.    You have been so amazing with all you have been going through.  May your faith, the love of your family and your zest for life continue to give you the strength to fight this horrid beast.  Please know that all of our arms will hold you up throughout this. 

Linda

Tlym

TxJunebug-You are welcome to join us on the Novemebr chemo thread. Lots of support from ladies going through the same!

borntosurvive

My heart is heavy with the news of Luv.  I am praying for you and sending you positive, healthy vibes.  You're and anchor to our group and a wealth of strength and an inspiration.  Stay strong and carry on my friend.  Thinking of you and your whole family.  HUGE hugs

NavyMom

Dear Luv and Lovin:  hope you can feel all our arms around you as you battle forward.  We are here and cirling the wagons... GROUP HUG, LADIES!

NavyMom

Thank you all for your support.  PET is tomorrow with f/u appt with Onc on Monday.  She did say if all is clear she will call and give me the news over the phone instead of coming in for the appt.  I am trying my hardest to just keep moving forward and think positive thoughts.

LuvRVing

Thanks to you all.  My fingers don't want to cooperate but please know that I am reading.

christina1961

NavyMom, thinking of you. I'm glad you will be able to get the news over the phone. I get very anxious with scans and you are courageous to get things checked out. 

borntosurvive

Good luck NavyMom.  Let us know what you find out xo

YoungMomToronto

I am 42, new to the forum. Diagnosed 4 months ago. Mastectomy. Will start chemo in 2 days. AC-T-DD with Neupogen. 1.8cm IDC, 14cm DCIS, 0/6 lymph nodes. 3 children between age 7 to 11 are my motivation to survive.

Planning to do tram flap reconstruction (tunnel under skin) after chemo. Afraid of recurrence at incision line. Does anyone know if this type recon gets in the way of recurrence check up?

Hopex3

Hi everyone!



I know I'm new to this thread and don't post very often but I want you all to know that I am here for all of you with thoughts and prayers!



Luv and Babs37... My arms are around you both and the rest of your family!



Navy mom....thinking of you tomorrow.



BernieEllen...as always your sense of humor is just what I needed today! Thank you



I just finished AC Thursday and have had no energy. Today is the first time I stayed home from work but I was such a blubbery mess, there was no way I could work. Does this happen to any of you? I slept and cried all day. Have the chills, took my temp and it was 99.1. I know that's not really a fever. Oh, and Inmate, I had some vivid dreams this afternoon. I hope to be better tomorrow.



Anyways, I hope everyone gets a good night sleep!



Erin

LuvRVing

By the way, a special shout-out to Inmate (Dawn).  I hope you are hanging in there

!

DesertMama

(((Luv))) Hugs and more hugs!

Cocker_Spaniel

Dear LUV my heart is so heavy at this crap news.  You have been a rock for us all with your strength,  positivity, humour and heaps of information whenever we have needed it.  Now we are here for you every minute of the day throughout your treatment.  I hope it kicks that cancers butt so hard it won't ever think of coming back.  Sending you and your family love and prayers. 

Everyone on here seems to be having troubles lately with chemo (again), tests, results,  pain and worries. I think of you all each and every day and send lots of love and warm gentle hugs to you all. Together we will stay strong and beat this sucker.

I had a letter from the hospital today concerning my abdominal and liver scan which is on the 23rd November exactly  a year to the day of my surgery. Oh boy, here we go again.   Plus I have to have a mammo on my right boob but have been dragging my feet on making the appointment. Guess with all you brave ladies on here I am going to have to pluck up the courage and go for it.   Love to all you courageous ladies.  Annie

BernieEllen

journey4life

Luv - well damn it! I too hoped it was a side effect of the clinical trial drug(s). I'm sending strength and courage so you can fight this f^cking disease. Know that we're all here for you and are surrounding you with love.

Lovin - a special hug for you as you support and love your mom through this. We'll be here for you too.

I HATE CANCER!

fhny2012

Luv and LovingMyMom - I don't post that much, but I just wanted to say that I am thinking of you both and sending all my positive thoughts and prayers your way. 

Wrenwood47

Thought this might cheer everyone up....so sorry for the mets that are still invading our lives. Be strong ladies!

Paul Newman
Only women of a certain era will fully appreciate this.... True story. (If you don't understand this, tell your mother, she'll get it!)
A Michigan woman and her family were vacationing in a small New England town where Paul Newman and his family often visited.
One Sunday morning, the woman got up early to take a long walk.After a brisk five-mile hike, she decided to treat herself to a double-dip chocolate ice cream cone.
She hopped in the car, drove to the centre of the village and went straight to the combination bakery/ice cream parlour.
There was only one other patron in the store: Paul Newman, sitting at the counter having a doughnut and coffee.
The woman's heart skipped a beat as her eyes made contact with those famous baby-blue eyes.
The actor nodded graciously and the star-struck woman smiled demurely.
Pull yourself together! She chided herself. You're a happily married woman with three children, you're forty-five years old, not a teenager!
The clerk filled her order and she took the ice cream cone in one hand and her change in the other. Then she went out the door, avoiding even a glance in Paul Newman's direction.
When she reached her car, she realized that she had a handful of change but her other hand was empty. Where's my ice cream cone? Did I leave it in the store? Back into the shop she went, expecting to see the cone still in the clerk's hand or in a holder on the counter or something! No ice cream cone was in sight.
With that, she happened to look over at Paul Newman. His face broke into his familiar,warm,friendly grin and he said to the woman,

"You put it in your purse."

 

mags20487

Luvrving...i am so so sorry to hear this news...i have followed you ( secret stalker) and have always enkoyed your posts..keep fighting!



I am out of hospital after my marathon almost eleven hr surgery. They look pretty good..leftie got infection so lots of antibiotics..see doc thurs for post op...hoping all will be good to come home

OBXK

Annie - be brave! Think of how good peace of mind will feel.



Hopex3 - the steroids wreck havoc on my emotions. I hope you are feeling better soon.



Bernie - loved it!



Tomorrow I go for my second treatment. Last week it was gemzar/carbo this week, just gemzar. DH just picked up my neulasta shot from the Rx - he's going to give it to me Friday here at home. Not looking forward to that shot from hell.



I've ordered myself a new set of sheets, duvet and mattress topper.

Loving my new adjustable bed, just need an over the bed tray table and I'll be set!



DH bought me a new tablet to take to chemo, because I can't get my

iPod to connect In the infusion

room.



Ground chuck was on sale, so I'm making black bean & beef burritos

for dinner. Teaching DH, all my old standby dinners.

Big hugs all around!!!

Anonymous

http://www.oncologystat.com/journals/journal_scans/Thymosin_Beta_15A_TMSB15A_is_a_Predictor_of_Chemotherapy_Response_in_Triple_Negative_Breast_Cancer.html

Anonymous

Thymosin Beta 15A (TMSB15A) is a Predictor of Chemotherapy Response in Triple-Negative Breast Cancer

Br J Cancer. 2012 Oct 18;[Epub Ahead of Print], S Darb-Esfahani, R Kronenwett, G von Minckwitz, et al

TAKE-HOME MESSAGE

Investigators validated thymosin beta 15A levels as predictive of response to neoadjuvant chemotherapy in patients with triple-negative breast cancer.

Abstract

Background: Biomarkers predictive of pathological complete response (pCR) to neoadjuvant chemotherapy (NACT) of breast cancer are urgently needed.

Methods: Using a training/validation approach for detection of predictive biomarkers in HER2-negative breast cancer, pre-therapeutic core biopsies from four independent cohorts were investigated: Gene array data were analysed in fresh frozen samples of two cohorts (n=86 and n=55). Quantitative reverse transcription polymerase chain reaction (qRT–PCR) was performed in formalin-fixed, paraffin-embedded (FFPE) samples from two neoadjuvant phase III trials (GeparTrio, n=212, and GeparQuattro, n=383).

Results: A strong predictive capacity of thymosin beta 15 (TMSB15A) gene expression was evident in both fresh frozen cohorts (P<0.0001; P<0.0042). In the GeparTrio FFPE training cohort, a significant linear correlation between TMSB15A expression and pCR was apparent in triple-negative breast cancer (TNBC) (n=61, P=0.040). A cutoff point was then defined that divided TNBC into a low and a high expression group (pCR rate 16.0% vs 47.2%). Both linear correlation of TMSB15A mRNA levels (P=0.017) and the pre-defined cutoff point were validated in 134 TNBC from GeparQuattro (pCR rate 36.8% vs 17.0%, P=0.020). No significant predictive capacity was observed in luminal carcinomas from GeparTrio and GeparQuattro.

Conclusion: In TNBC, thymosin beta 15A, TMSB15A gene expression analysis might help to select patients with a high chance for pCR after NACT.

JAN69

Karen - Good luck teaching DH how to cook.  My efforts  to do that were a disaster.  Your bed setup sounds wonderful.  I sure hope all your chemo tx are easy on you.

Heidi - Thanks for the information.  I wonder how this will be applied to ca patients.

I check in on the web site Positives about Negatives.  She often has interesting TNBC tidbits.

Finding joy today.......Jan

LynnME

I, like some of the other wonderful ladies on here don't post much, but stalk often and I constantly think of all of you during the day.  I don't belong to a support group in person, this site and all of you are my support group. 

My heart was saddened with Luv's news, but please know, you are in my heart and thoughts.  You have always given so much of yourself.  I am sending positive thoughts, hugs and emotional support your way for you and your family. 

Dawn the same goes to you too...Fight with every ounce of your being and all of us will be beside you all the way...

ksmatthews

Inmate I remember having nightmares about roller coasters while doing chemo.  No dreams..

Luv so sorry to hear of your dx, I am praying that radiation zaps those little mets! And thank you to your daughter for posting and keeping us all up to date.  

ruth so sorry to hear about your mouth pain, praying it is nothing cancer related

Sugar77

Luv - thinking of you.

Inmate - so glad to hear from you.

Ruth - thinking of you and praying there's nothing serious going on with your jaw.

Hello everyone....just wanted to check in to see how everyone's doing.

melissa119

Hi ladies!

Haven't posted in awhile but I am always reading your posts! My thoughts and prayers are with everyone facing recurrences. I know you will give your all to beat ca's ass!!

Just wanted to say that although I don't post often I find comfort in reading your posts and feel like I am not fighting this alone. I don't think I could have gotten through this year without having you all there. And now tomorrow I close a really difficult chapter in this journey as I am having my last taxol treatment and will be done with chemo! 16 treatments done... Never thought I'd say that. Seemed so far ahead looking back to June when treatments started. But it's finally here and I pray I never have to face it again :-).

OBXK

Melissa - wonderful news! I hope it's an easy one.

DesertMama

Melissa, congrats on reaching the end of this chapter- onwards and upwards!

Hopex3, I suffered from terrible depression during AC treatments, just filled with doom and gloom. I had to remind myself not to speak to my mom during a certain time period after infusions. I wasn't sure if it was the chemo, or the early onset of chemopause (although one rather bitchy friend keeps reminding me that I am 45 so it is not really early in her opinion!), or a combination of the 2. The depression got a lot better with the switch to taxol, even though I didn't tolerate that regimen for other reasons and have since been changed to taxotere.

OBXK and Luv, the new regimens are going to blast those mets into oblivion! Stay strong lovely ladies! xo

YoungMom, welcome to the board. Sorry you are here, but happy you found us!

Mags, congrats on the new girls! Fingers crossed your leftie has a speedy recovery from the infection.

Inmate, sorry you are missing your sleeping dreams. Keep on believing you can fly and visualize it during your daydreams instead. xoxo

borntosurvive

Inmate:  I remember having some pretty "steamy" dreams while on chemo.....could have been the steroids or could have been that I was reading 50 Shades?!  Hard to say.  Hope you're in dreamland again soon my Dear.

I am friends with Mags on FB and she wrote that her left one did not take so she's back in surgery today.  Thoughts and prayers that this one goes better. 

Melissa:  Ring that bell loud and proud.  Congrats on being done.

Gentle hugs to you all today.  Off to make lunch for my JK kid and head to work.  LOVE xo