HER2

patti4511
patti4511 Member Posts: 180
edited June 2014 in HER2+ (Positive) Breast Cancer

Can someone be HER2-- the first time diagnosed and then if a recurrece comes back be HER+

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  • lexislove
    lexislove Member Posts: 2,645
    edited January 2010

    Yes.

    Sometimes when a woman has a recurrence, the tumor pathology can change or it can be the same as the initial diagnosis.

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  • BorneoMom
    BorneoMom Member Posts: 38
    edited January 2010

    I saw my doctor today and he gave me some medical/technical info I requested about HER2 treatment. So I just read that yes, metastasis can be HER2+ when the original was not.

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  • suzieq60
    suzieq60 Member Posts: 6,059
    edited January 2010

    Patti,

    Could be a new cancer not a spread of the original.

    Sue

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  • DianeKS
    DianeKS Member Posts: 241
    edited January 2010

    Hi Patti,

    What a coincidence that you posted this today. I was just told today that I am Her2 +ve after a recurrence in Sept.2009 when at diagnosis I was -ve in 2006.  My kids are now in bed so I hopped on this forum to find out as much as I can about herceptin and what others have experienced.  Confused still and disappointed about treatment for another year.  The oncologist I saw today (not the Dr. I normally see) stated that it happens in about 20% of recurrences. BTW  I was ER+/PR+ at diagnosis and now ER+/PR-

    Anyone else have a change in their results after a recurrence?  Is that what has happened to you Patti?

    Just starting to research so any advice would be appreciated.

    Thanks, Diane

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