Dr. Nobuto Yamamoto

juliebb

Report this PostPost a replyJan 22, 2009 12:19 pmDanielle1 wrote:Post a reply2 minutes ago Danielle1 wrote:Please read this article. A cure for metastatic Breast cancer and colon cancer was found to be 100%. Although the number of patients used was small, I find this to be remarkable. How many more people are we going to let suffer!! I wish I knew how to bring this to light. I suppose at this point all I can do is bring it to the attention of as many people as possible.  Please read article below. Dr. Nobuto Yamamoto also has articles published in Cancer Immunology and Immunotherapy journal. I was unsure if this information was false and so attempted to look up the articles myself at the University of Michigan Health Science Library, i found them. http://www.lewrockwell.com/sardi/sardi84.htmlGod Bless I copied this from the Palliative Care board. I asked Danielle1 to post it here, but don't think she got my message. What do you think? Sincerely,Julie 

LisaF

Hope it is true!  However, I did a quick google search and found that the same doctor says this is the cure for HIV also.  Makes me a little wary.

orange1

Very Interesting.  Thanks for posting.

Now lets hope some greedy pharmaceutical company buys the rights, studies it extensively and gets it to market soon.

Anonymous

Yes, thank god for the greedy pharmaceutical companies !

Yazmin

I would love for this to be true, but if its sounds too good to be true..........

crazy4carrots

I expect that immunologists are looking at this very seriously and we'll eventually see the results of further studies.  By the way, there is a strong correlation between cancer, autoimmune disorders and AIDS -- all being immune-system disorders -- so this may very well work for AIDS as well.  Wouldn't that be wonderful!  And the fact that his work has been published in highly respected journals means that his peers in the scientific community do indeed take it very seriously.

But, research does take a long time -- this scientist's results need to capable of being duplicated by others before they are validated.

Anonymous

Typically, 10 years or more for a promising lab result to become a product.

vivre

Thanks for sharing this article Julie. It is always great to see new glimmers of hope.

Husband11

Very interesting.  Here is some discussion on it from a UK website.  It seems to shed some light on interpreting the results.  The metastatic part may not be exactly what we would call metastatic, there was no observation of metastatic tumour themselves, but rather a measure of a blood indicator of micrometastasis believed by Yamamoto to be indicative of disease vs cure.  More like patients in remission being speculatively "cured".  Still sounds promising.

 http://scienceblog.cancerresearchuk.org/2008/12/03/cancer-cured-for-good-gc-maf-and-the-miracle-cure/

orange1

Timothty -

Thanks for an excellent post.

07rescue

Thanks, Timothy!

Yamamoto is clearly a controversial figure. I am going to follow up and contact him. Philadelphia is not so far away that I couldn't go meet with him and see what his future clinical trial plans are, perhaps when my chemo is over and I'm in better shape physically.

This thread is exactly the kind of interesting and civl discussion that I would love to see more of on this board. I really appreciate when someone actually takes the time to look into a subject and bring the results into our conversation, as opposed to posting brief, snarky comments that add zero enlightenment to the discussion, only adding hostility and flames, and derailing the discussion. I personally would love to see both conventional and alt/comp treatments receive respectful discussion, as both likely have their place.

The last nurse who administered my chemo at the cancer center where I am receiving treatment has been doing oncology for 12 years, and she was the first to say that there is no interest in finding a cure for cancer, because the entire field is based on constant treatment provision. Her job, and everyone else's,depends on prolonged treatment of cancer patients, and a tremendous amount of revenue is at stake for medical institutions. They often base provision of care for less well remunerative conditions, and treatment of the poor and uninsured on the more lucrative specialties, such as cancer care. The oncologists themselves often don't make much more than other physicians, but the radiology scans and infusion procedures are very well reimbursed. All the incentives are perverse in this system of care.

Perhaps if primary care were more respected and properly reimbursed there wouldn't be such a need to offset expenses by promoting noncurative procedure based care in the other specialties.

It is such a complex and chaotic web we weave, in healthcare. 

konakat

As a Stage 4 I'm thankful for the chemo and rads I've gotten and am getting  -- they're keeping my cancer at bay for now.  If I wasn't getting chemo I wouldn't be here.  I'd rather have the toxins of chemo running amuk in my body attacking my cancer than letting cancer cells having a free-for-all.

For some in early stage, chemo and rads can "cure" in that they irradicate the body of cancer.  My Mom and many long term survivors are proof of this. For for others chemo is more managing a chronic disease (i.e., my situation).  Sure, eventually the treatments will run out -- in the meantime I count on the current and new, proven discoveries and clinical trials. if there are some alternative or co-therapies that work to strengthen my body, great -- that's why I regularly visit this board to see what's what.

As to the healthy debate -- I love it -- it keeps us informed, and thinking.

Elizabeth

FloridaLady

Effects of Vitamin D₃-Binding Protein-Derived Macrophage Activating Factor (GcMAF) on Angiogenesis

Shigeru Kanda, Yasushi Mochizuki, Yasuyoshi Miyata, Hiroshi Kanetake, Nobuto Yamamoto

Affiliations of authors: S. Kanda, Department of Molecular Microbiology and Immunology, Division of Endothelial Cell Biology, and Department of Urology, Nagasaki University Graduate School of Medicine, Nagasaki, Japan; Y. Mochizuki, Y. Miyata, H. Kanetake, Department of Urology, Nagasaki University Graduate School of Medicine; N. Yamamoto, Socrates Institute for Therapeutic Immunology, Philadelphia, PA.

Correspondence to: Shigeru Kanda, M.D., Ph.D., Department of Molecular Microbiology and Immunology, Division of Endothelial Cell Biology, Nagasaki University Graduate School of Medicine, 1-7-1, Sakamoto, Nagasaki 852-8501, Japan (e-mail: shigeruk@net.nagasaki-u.ac.jp ).

Background: The vitamin D₃-binding protein (Gc protein)-derivedmacrophage activating factor (GcMAF) activates tumoricidal macrophagesagainst a variety of cancers indiscriminately. We investigatedwhether GcMAF also acts as an antiangiogenic factor on endothelialcells. Methods: The effects of GcMAF on angiogenic growth factor-inducedcell proliferation, chemotaxis, and tube formation were examinedin vitro by using cultured endothelial cells (murine IBE cells,porcine PAE cells, and human umbilical vein endothelial cells[HUVECs]) and in vivo by using a mouse cornea micropocket assay.Blocking monoclonal antibodies to CD36, a receptor for the antiangiogenicfactor thrombospondin-1, which is also a possible receptor forGcMAF, were used to investigate the mechanism of GcMAF action.Results: GcMAF inhibited the endothelial cell proliferation,chemotaxis, and tube formation that were all stimulated by fibroblastgrowth factor-2 (FGF-2), vascular endothelial growth factor-A,or angiopoietin 2. FGF-2-induced neovascularization in murinecornea was also inhibited by GcMAF. Monoclonal antibodies againstmurine and human CD36 receptor blocked the antiangiogenic actionof GcMAF on the angiogenic factor stimulation of endothelialcell chemotaxis. Conclusions: In addition to its ability toactivate tumoricidal macrophages, GcMAF has direct antiangiogeniceffects on endothelial cells independent of tissue origin. Theantiangiogenic effects of GcMAF may be mediated through theCD36 receptor

luv_gardening

Another piece of the puzzle.  Dated March 2011, so someone is still studying Gc-MAF.

http://aras.ab.ca/articles/scientific/icar2011/3-Punzi-Morucci.pdf

http://www.gcmaf.eu/info/

Srh242

Any one taking gcmaf. ?

exbrnxgrl

srh242,

This thread has been inactive for almost 3 years. You might have a better response if you started anew thread on the topic.

Srh242

Ok,thank u