vitamin C... read this

mginger

http://www.mcgill.ca/newsroom/news/item/?item_id=19302

bmdaley

Thanks for posting this, it peaked my interest and I found this (abstract below). You can get full article in Proceedings of the National Academies of Sciences (http://www.pnas.org) by searching by title of article. 

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice.

Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M.

Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, and Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Ascorbic acid is an essential nutrient commonly regarded as an antioxidant. In this study, we showed that ascorbate at pharmacologic concentrations was a prooxidant, generating hydrogen-peroxide-dependent cytotoxicity toward a variety of cancer cells in vitro without adversely affecting normal cells. To test this action in vivo, normal oral tight control was bypassed by parenteral ascorbate administration. Real-time microdialysis sampling in mice bearing glioblastoma xenografts showed that a single pharmacologic dose of ascorbate produced sustained ascorbate radical and hydrogen peroxide formation selectively within interstitial fluids of tumors but not in blood. Moreover, a regimen of daily pharmacologic ascorbate treatment significantly decreased growth rates of ovarian (P < 0.005), pancreatic (P < 0.05), and glioblastoma (P < 0.001) tumors established in mice. Similar pharmacologic concentrations were readily achieved in humans given ascorbate intravenously. These data suggest that ascorbate as a prodrug may have benefits in cancers with poor prognosis and limited therapeutic options.

FloridaLady

There is a lot of info of Vitamin C and cancer.  There is a new study out last year where they saw positive things again but they are also finding out that it depends on what kind of cancer you have if this will work. And of course they have not gotten that far. This argument has been going on for about forty years. They just can't make up their minds. This is a big part of some alternative protocol for treating cancer.

Flalady

mginger

 

    Yes, I know that this argument (I think Nobel prize Pauling  is one of the pioneers) has been going for quite a while but... why on earth does it take that long to get answers?

FloridaLady

That is the million dollar question with so many things I read about. 

nellski

Probably because Vitamin c isn't going to make a huge pharmecuetical any money

Anonymous

Why won't it Nellski? What economics make it impossible for a "huge pharmaceutical" company to make money on Vit. C, but supplement companies manage to make a fortune on it?

lisasayers

Nellski.....don't bite.  Just let it go!

anondenet

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Has anyone tried the nanotechnology Vitamin C? There are a number of products. Any opinions?