High alkaline phosphotase and Herceptin

tomatojuice

Was wondering if anyone else has had somewhat high alkaline phosphotase levels while on herceptin? I have three more treatments to go. Will be finished with a year in May of Herceptin. My alk phosphotase levels have been high.

mmm5

Hi my alk phos levels not high, but my ALT has been high and I have atributed that to many meds. (Herceptin, Arimidex, etc)

mmm5

tomato juice

How have your white counts been on Herceptin?

Anonymous

Tomatojuice, what do you call "high"?

tomatojuice

hi LJi3 and mm5    I have had no trouble with my white counts. They stayed within normal ranges. When I say my alkaline phosphotase is high- I mean that for me normal was between 81 and 95. But since starting chem on 4/ 08 they went up 20 points to 120. I finished chem , but get herceptin every 3 weeks and they have stayed consistently between 109 and 131. I am having a ct next week to determine what could be causing the elavation. But I just have this gut feeling that its the herceptin, and I am beginning to worry about liver damage. I just read a case report of a woman who had to go off herceptin because of elevated alk ph. I am starting to worry, because I don't know how high your levels would have to be before they would consider discontinuing the herceptin. Also I don't think there is much data about this, even for the doctors. That is why they are sending me for a ct, because they think it might be something else. Maybe I will call my doctor tomorrrow to find out how serious this elevation of alk ph is.I am freaking out, have been all day and yesterday.

mmm5

Tomatoe juice my ALT has become higher not ALK phos, talked to my onc yesterday and she stated that it is all the medication, going through the liver. (Herceptin, Zometa, and AI)