Ductal and lobular same breast, same time?

DoubleMammyWhammy

Hi,

Anyone else have 2 different types of cancers at the same time?  I was diagnosed with invasive ductal first then another mass was found during a breast MRI and it was lobular ductal.  Second finding was tougher though I'm thankful we found it since I had a lumpectomy scheduled and it would have been the wrong option for me!

Just recovering from bilateral mastectomy & DIEP flap reconstruction and meeting with oncologist 1/5 to determine what treatment options are available.   Both are similar her2 positive, etc so they should respond well to the same treatment, but will I need more since I have this Double Mammy Whammy?

 I could find very little anywhere else on the web and I'm a geek so please help me if you have any info!

 thanks!

leaf

I don't think its actually that uncommon.

Have you checked out Pubmed? http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed

http://www.breastcancer.org/symptoms/path_report/ask_expert/question_08.jsp

This woman had ductal with lobular tendencies. http://www.breastcancer.org/pictures/reconstruction/photo_nipple_recon.jsp

 "Li, from the Fred Hutchinson Cancer Research Center in Seattle, and colleagues note that invasive ductal carcinoma is still the most common type of breast cancer in the US (about 70 percent of cases), but invasive lobular and mixed ductal-lobular carcinomas now make up about 16 percent of cases. As they report in the journal Cancer Epidemiology, Biomarkers, and Prevention, the researchers conducted a population-based study that included 324 women with lobular, 524 with ductal, and 196 subjects with ductal-lobular breast cancer who were diagnosed between 2000 and 2004." http://www.breastcancer.org/risk/new_research/20080115.jsp

Gitane

I had DCIS and pleomorphic Invasive Lobular Carcinoma.  This isn't the same as having IDC and ILC. The ductal part was "in-situ" and the invasive part was pleomorphic lobular.  Still,  it is two different types. I don't know if this is the same as what the above article calls mixed ductal-lobular.  There were many foci of tumor in my left breast, only, but  I had bilat. mast., also. I was using HRT, so there may well be a connection there as mentioned in the article leaf listed.  

I'm sorry you got the Double Whammy.  I hope the surgery and treatment is just what you need to be rid of this forever.

dlb823

Hi, Double ~  My bc was kind of complex.  My original biopsy called my bc ductal with lobular features.  The pathology from my lumpectomy for that lesion described it as mixed ductal & lobular (adjacent tumors). They also found two distinct types of ductal cells in my sentinel node, so advised I probably had another yet unfound ductal tumor, and recommended a mast.  At that point I went to UCLA for a 2nd opinion, and on super high powered MRI they found another lesion that was tubular, and a 3rd lesion that was tubular-lobular.  One was in the same quadrant as lesion #1, the other was in a different quadrant.  The pathology from my mast. (w/Diep flap) at UCLA disclosed yet another microscopic (1mm) lesion that was lobular.  I haven't read the article leaf referenced, but I'm anxious to and will tomorrow (it's late here now).  My sister also had mixed ductal & lobular bc, although I don't have the exact details.  In my case, since I am otherwise extremely healthy, I feel strongly that HRT was key in my developing bc, and I have been curious to know if others, especially with this mixed ductal-lobular dx, were also on HRT, although my sister was not.    Deanna

DoubleMammyWhammy

Hi Leaf, Gitane and dlb823,

Thanks for your replies.  Those are both very complex!  I'm 38 and not on HRT, but there still could be a connection.   For me it is very reassuring to learn as much as I can so I appreciate the article reference.  Now that I know what to research, I'll be able to find more info.  I was looking at "unilateral synchronous" bc and found a few things. 

sunflower45

I had a lumpectomy in September because the biopsy showed DCIS.  But then the pathology on the lump also showed I had small amounts of ILC so I had a mastectomy in November with node dissection.   The ILC had spread to two nodes and the oncologist said I was fortunate because the DCIS  shows up on mammograms while ILC is often not detected until it is very large.  Any combination is possible.   The important thing is getting it diagnosed and treated as soon as possible.

Snowbird

Yep, count me in. Biopsy results said "invasive lobular" but after mastectomy the pathology report included a finding of ductal as well...  surprise!  I had been on HRT off & on for a while shortly after menopause and would like to think that THAT's the reason I have this now vs. some other, unknown, reason...  According to my onc., the treatment for the lobular stuff will take care of the ductal stuff too, so no change in my treatment plan as a result. TC*4, one down, 3 to go.

Happy New Year!

jrgolomb

Hi.  I was initially diagnosed with cancer called tubular carcinoma-5 mm.  After a mri, they found a mass near my nipple.  Subsequent surgery and path reports found dcis-cribiform and dcis lobular cancer-all very small.  The snb became a axillary node dissection because the doctor uncovered idc.  Tubular carcinoma and cribiform are subtypes of idc, slower of the idc,but because the idc-most aggressive type- was found in a node I will be treated accoridng to that type.  Not sure which is most effective- the Tc / or AC or Tac or if i need something totally different. I am multifocal as well.