Late recurrence and tumor grade

sam52

I have a good friend who is a bc onc in Sweden. When we spoke recently we were talking about late recurrences (mets) and he seemed to imply that grade 3 tumors tend to recur in the first 2 years after dx and are less likely to recur after 5 years.
Does anyone have any input into this?

Thankyou,

Sam

fd411

In my particular situation, he's spot on. I was diagnosed with mets May 4 2007. My original diagnosis date was April 11, 2006. My tumors were/are grade 3.

SandyInNJ63

Sounds good to me, if it has merit. I had grade 3 tumors and I'm just coming up on my 5 year mark next month.

iodine

My onc and I have discussed this as well, that most recurrances are identified in the first 2 years or so after dx.

wallan

Well, this is good news for me. I had a grade 3 tumor.

I have been NED now for 3 years and 3.5 months.

Wendy A

sam52

I am so interested in this.....please could someone tell me how to do a poll?

Thanks,
Sam

sam52

Bumping.......

I would like to do a poll on this, if it's still possible.

If not, anyone else got any input?

Thanks,

Sam

BethNY

I dont know if it has to do with grade, I just know my onc said time for most likely to recur is the first two years out.

I'm grade three with no recur at 3.5 yrs out

Member_of_the_Club

I have heard that for triple negative, grade 3, it is most likely to recur in the first two years. Women who are er/pr+ like myself are on the hook for much, much longer. We are the ones most likely to have the late recurrences.



There's gotta be studies somewhere. Have you asked Dr. Google?

Pharmmom

I had grade 3 in 2002.  No recurrance and its 2007.  Sounds good to me.  

Sierra

I am Grade 3

coming up to 8 yrs

node positive



and .. my onc told me..



He can keep it at bay

but he can not cure me



feeling v. blessed



Best to you Sam





)

mkl48

That is true for ER_ or Her + , but not as true for er+.Beth

mkl48

I wonder why he said that if you are not stage 4? It seems as though you are ER- so the more time passes the more likely a disease free for many years even if he won't say cure.Beth

LuAnnH

I'm not sure what my original grade was but my mets showed up 8 years later   I really don't believe anyone knows why anyone gets a recurrance or mets.  If they knew that we wouldn't have this problem

sam52

He was implying that most recurrences (meaning mets) happen in the first 2 years, particularly for grade 3 tumors.I don't think anyone would argue with that. But that 'late' recurrences - ie after 6 years or so, are more likely to be  grade 1 tumors, since they are slow-growing and often lie dormant.

I was wondering if there is any truth in this, based on experiences of sisters here on these boards.

No-one is saying that this is a reason why anyone gets mets, as there are obvoiusly so many other factors involved.

Sam

Beesie

Overall, most recurrences happen within the first 3 years, after that the annual risk declines but it remains significant for about 10 years.  After about 10 years, there is still some risk but by that time it's quite small.  Here's an article about recurrence risk, including a chart that shows the rate of recurrences by year post-surgery.

http://www.gaeainitiative.eu/word_page/BC_Recurrence.htm

Member_of_the_Club

This is really interesting but it refers to women who have not received adjuvant therapy. Is there a similar chart for women who have received treatment? Also, I'm wondering what level of risk I have -- one positive node and her2neu negative -- seems to be floating between intermediate and high risk. Upper-middle-class risk?